1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide

Base Information

Chemical Name:1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide
CAS No.:32866-51-6
Molecular Formula:C16H14N2O2
Molecular Weight:266.299
Hs Code.:
DSSTox Substance ID:DTXSID50496893

Synonyms:32866-51-6;DTXSID50496893;1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide

Suppliers and Price of 1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:266.105527694
Heavy Atom Count:20
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C(C1=O)C(=O)NC3=CC=CC=C3

Technology Process of 1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide

There total 2 articles about 1-Methyl-2-oxo-N-phenyl-2,3-dihydro-1H-indole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61-70-1
N-methyl-2-indolinone

: 103-71-9
phenyl isocyanate

: 32866-51-6
1-methyl-2-oxo-N-phenylindoline-3-carboxamide

Guidance literature:: N-methyl-2-indolinone; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.166667h;

phenyl isocyanate; In tetrahydrofuran; at 0 ℃;
DOI:10.1055/s-0037-1611782

Reference yield:

: 32866-51-6
1-methyl-2-oxo-N-phenylindoline-3-carboxamide

Guidance literature:: Phenylisocyanat, 1-Methyl-2-oxo-indolin;
DOI:10.1016/S0040-4039(01)84761-4

Reference yield: 93.0%

: 32866-51-6
1-methyl-2-oxo-N-phenylindoline-3-carboxamide

: 89320-02-5
4-methoxy-N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide

: 3-(2-hydroxy-5-(4-methoxyphenylsulfonamido)phenyl)-1-methyl-2-oxo-N-phenylindoline-3-carboxamide

Guidance literature:: 1-methyl-2-oxo-N-phenylindoline-3-carboxamide; With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((S)-1-oxo-3-phenyl-1-((1R,2R)-2-(pyrrolidin-1-yl)cyclohexylamino)propan-2-yl)thiourea; In chloroform; at -30 ℃; for 0.5h;

4-methoxy-N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide; In chloroform; at -30 ℃; for 1h; enantioselective reaction;
DOI:10.1055/s-0037-1611782