61-70-1Relevant articles and documents
Thermally induced reaction of diazoamides with isatins: A complementary approach to the 3,3′-bioxindole derivatives
Zheng, Yang,Bao, Ming,Qiu, Lihua,Xu, Xinfang
, p. 3390 - 3393 (2017)
An efficient and thermally induced reaction of diazoamide with isatin under mild reaction conditions is described, which provides a complementary approach to the 3,3′-bioxindole in high yields with excellent diastereoselectivity. In comparison to the metal-catalyzed versions, this is the only example under catalyst-free conditions via a non-carbene reaction pathway.
Reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehydes with barbituric acids and 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Formation of compound with extremely short intramolecular hydrogen bond in eight-membered pseudocycle
Suzdalev, Konstantin F.,Babakova, Maria N.,Kartsev, Victor G.,Krasnov, Konstantin A.
, p. 64 - 75 (2015/05/12)
New indolin-2-one derivatives, containing in its molecules eight-membered pseudo-cycle with unusually short intramolecular hydrogen bond in OHO-bridge have been synthesized by reaction of 2-chloro-1-alkyl-1H-indole-3-carbaldehyde with barbituric acids or 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one. Under the action of amines they undergo fragmentation to 5-aminomethylenebarbituric acids or 4-aminomethylenepyrazolones and 1-alkyl-1,3-dihydroindol-2-ones.
Selective photo-reduction of 1-alkylisatins in degassed alcoholic solutions
Tatsugi, Jiro,Ikuma, Kenji,Izawa, Yasuji
, p. 7 - 10 (2007/10/02)
Irradiation of 1-alkylisatins (1) in degassed alcohols afforded 1-alkyl-3-hydroxyoxindoles (2) and 1-alkyloxindoles (3) as chemoselective photoproducts.
