1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl-

Base Information

Chemical Name:1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl-
CAS No.:77094-09-8
Molecular Formula:C₁₁H₁₀N₄
Molecular Weight:198.227
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00227876
Wikidata:Q83107716
Mol file:77094-09-8.mol

Synonyms:77094-09-8;1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl-;5-methyl-3H-imidazo[4,5-f]quinolin-2-amine;5-Methyl-1H-imidazo(4,5-f)quinolin-2-amine;DTXSID00227876

Suppliers and Price of 1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
5-methyl-1H-Imidazo[4,5-f]quinolin-2-amine 97.00%
25G
$ 8510.00

AccelPharmtech
5-methyl-1H-Imidazo[4,5-f]quinolin-2-amine 97.00%
5G
$ 4530.00

AccelPharmtech
5-methyl-1H-Imidazo[4,5-f]quinolin-2-amine 97.00%
1G
$ 2640.00

Total 1 raw suppliers

Chemical Property of 1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl-

Chemical Property:

Vapor Pressure:5.91E-10mmHg at 25°C
Melting Point:246-248 °C (decomp)
Boiling Point:495.4°C at 760 mmHg
PKA:13.88±0.40(Predicted)
Flash Point:285.6°C
PSA：68.32000
Density:1.405g/cm³
LogP:1.93180
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:198.090546336
Heavy Atom Count:15
Complexity:245

Purity/Quality:: 5-methyl-1H-Imidazo[4,5-f]quinolin-2-amine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C3=C1N=CC=C3)N=C(N2)N

Technology Process of 1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl-

There total 6 articles about 1H-Imidazo(4,5-f)quinolin-2-amine, 5-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

: 506-68-3
bromocyane

: 77094-08-7
5,6-diamino-8-methylquinoline

: 77094-09-8
2-amino-5-methyl-3H-imidazo<4,5-f>quinoline

Guidance literature:: In water; for 2h;
DOI:10.1246/bcsj.55.2233

Reference yield:

: 77094-04-3
6-amino-8-methylquinoline

: 77094-09-8
2-amino-5-methyl-3H-imidazo<4,5-f>quinoline

Guidance literature:: Multi-step reaction with 5 steps

1: 19 g / AcOK / ethanol / 2.5 h / Heating

2: 16.6 g / 61percent HNO₃ / 1 h / 70 - 80 °C

3: 3 g / conc. H₂SO₄ / 1 h / 95 °C

4: Fe, conc. aq. HCl / 0.33 h

5: 15 percent / H₂O / 2 h

With hydrogenchloride; sulfuric acid; nitric acid; potassium acetate; iron; In ethanol; water;
DOI:10.1246/bcsj.55.2233

Reference yield:

: 77094-05-4
8-methyl-6-(p-tolylsulfonylamino)quinoline

: 77094-09-8
2-amino-5-methyl-3H-imidazo<4,5-f>quinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 16.6 g / 61percent HNO₃ / 1 h / 70 - 80 °C

2: 3 g / conc. H₂SO₄ / 1 h / 95 °C

3: Fe, conc. aq. HCl / 0.33 h

4: 15 percent / H₂O / 2 h

With hydrogenchloride; sulfuric acid; nitric acid; iron; In water;
DOI:10.1246/bcsj.55.2233