2,4-Dichloro-6-isopropoxy-1,3,5-triazine

Base Information

• Chemical Name: 2,4-Dichloro-6-isopropoxy-1,3,5-triazine
• CAS No.: 6684-27-1
• Molecular Formula: C6H7 Cl2 N3 O
• Molecular Weight: 208.047
• Hs Code.: 2933699090
• European Community (EC) Number: 229-728-9
• DSSTox Substance ID: DTXSID00216962
• Nikkaji Number: J298.064I
• Wikidata: Q83093290
• Mol file: 6684-27-1.mol

Synonyms:2,4-Dichloro-6-isopropoxy-1,3,5-triazine;6684-27-1;2,4-dichloro-6-propan-2-yloxy-1,3,5-triazine;EINECS 229-728-9;2,4-dichloro-6-isopropoxy-[1,3,5]triazine;1,3,5-Triazine, 2,4-dichloro-6-(1-methylethoxy)-;SCHEMBL1968887;DTXSID00216962;AKOS012155099;AT13236;2,4-dichloro-6-isopropyloxy-1,3,5-triazine;2,4-dichloro-6-(propan-2-yloxy)-1,3,5-triazine

Chemical Property of 2,4-Dichloro-6-isopropoxy-1,3,5-triazine

Chemical Property:

• Vapor Pressure: 0.000184mmHg at 25°C
• Boiling Point: 339.1°C at 760 mmHg
• Flash Point: 158.9°C
• PSA: 47.90000
• Density: 1.383g/cm³
• LogP: 1.96560
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 206.9966172
• Heavy Atom Count: 12
• Complexity: 137

Purity/Quality:

99% ^*data from raw suppliers

2,4-DICHLORO-6-(PROPAN-2-YLOXY)-1,3,5-TRIAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC1=NC(=NC(=N1)Cl)Cl

Technology Process of 2,4-Dichloro-6-isopropoxy-1,3,5-triazine

There total 3 articles about 2,4-Dichloro-6-isopropoxy-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + isopropyl alcohol (67-63-0,8013-70-5) → 2,4-dichloro-6-isopropyloxy-1,3,5-triazine (6684-27-1)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; In benzene; at 80 ℃; for 32h;

DOI:10.1080/00397919408010229

Reference yield:

1,3,5-trichloro-2,4,6-triazine (108-77-0) + isopropyl alcohol (67-63-0,8013-70-5) → 2,4-dichloro-6-isopropyloxy-1,3,5-triazine (6684-27-1) + N-[4,6-dichloro-1,3,5-triazin-2-yl]-N-ethyl-N-isopropylamine

Guidance literature:

With N-ethyl-N,N-diisopropylamine; at 20 ℃; for 4h; Concentration; Time; Temperature;

Reference yield:

→ 2,4-dichloro-6-isopropyloxy-1,3,5-triazine (6684-27-1)

Guidance literature:

/BRN= 135423/;

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

isopropyl alcohol

Refernces

• 1、 -. "INDOLE AHR INHIBITORS AND USES THEREOF". Paragraph 00796-00797. . Retrieved 2018/11/22.
• 2、 Mibu, Nobuko,Yokomizo, Kazumi,Aki, Hatsumi,Ota, Norimasa,Fujii, Hiroyuki,Yuzuriha, Ai,Saneyoshi, Shiori,Tanaka, Aoi,Koga, Airi,Zhou, Jianrong,Miyata, Takeshi,Sumoto, Kunihiro. "Synthesis and antiviral evaluation of some C3-symmetrical trialkoxy-substituted 1,3,5-triazines and their molecular geometry". . p. 935 - 944. Retrieved 2016/02/03.