Welcome to LookChem.com Sign In|Join Free
  • or

108-77-0

Post Buying Request

108-77-0 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Cyanuric chloride Manufacturer/High quality/Best price/In stock
Cas No: 108-77-0
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality Cyanuric Chloride supplier in China
Cas No: 108-77-0
No Data 1 Kilogram 10000 Metric Ton/Year Simagchem Corporation Contact Supplier
Cyanuric chloride CAS NO.108-77-0
Cas No: 108-77-0
USD $ 1.0-3.0 / Metric Ton 1 Metric Ton 10 Metric Ton/Day Hebei yanxi chemical co.,LTD. Contact Supplier
Hot Sale Cyanuric chloride Cas 108-77-0 with high quality and factory price
Cas No: 108-77-0
USD $ 4.0-6.0 / Kilogram 50 Kilogram 1000 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Amadis Chemical offer CAS#108-77-0;CAT#A801923
Cas No: 108-77-0
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Cyanuric chloride
Cas No: 108-77-0
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Cyanuric chloride
Cas No: 108-77-0
USD $ 5.0-5.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Enke Pharma-tech Co.,Ltd. (Cangzhou, China ) Contact Supplier
Cyanuric chloride
Cas No: 108-77-0
USD $ 1.0-1.0 / Kilogram 1 Kilogram 1000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier
Factory Supply Cyanuric chloride
Cas No: 108-77-0
No Data 200 Gram 4000 Metric Ton/Day Ality Chemical Corporation Contact Supplier
1,3,5-Triazine,2,4,6-trichloro- / LIDE PHARMA- Factory supply / Best price
Cas No: 108-77-0
No Data 1 Gram 1 Metric Ton/Day LIDE PHARMACEUTICALS LIMITED Contact Supplier

108-77-0 Usage

Storage Characteristics

Ventilated, low-temperature ,dry storeroom.it is stored separately from oxidants,and alkali.

production method

Cyanuric chloride production process usually consists of two steps : chloride cyanogen polymerization and chloride cyanogen preparation . There are many ways to generate chloride cyanogen, such as the synthesis of methyl thiocyanate and chlorine, hydrocyanic acid is dissolved in chloroform and chlorine gas is put in to synthesize , hydrocyanic acid method, sodium cyanide, urea, hydrocyanic acid direct method of chlorine and cyanuric chloride and the like, the current production of industrial cyanuric chloride generally uses sodium cyanide and hydrocyanic acid as raw materials in two ways. 1. Sodium cyanide method : using sodium cyanide as raw materials after the reaction of chlorine and cyanuric chloride, it is polymerized to form cyanuric chloride, it is quenched,then after crystallization ,the product is obtained. Material consumption fixed: sodium cyanide 1073kg/t, chlorine 1700kg/t. 2. The method of hydrocyanic acid :with hydrocyanic acid as raw materials ,chloride cyanogen is produced by the reaction of chlorine, and then use polymerization to generate cyanuric chloride, quench, crystallize , the product is obtained. Material consumption fixed: hydrocyanic acid 500kg/t, chlorine 1200kg/t.

Purification Methods

TCT crystallises from CCl4 or pet ether (b 90-100o) and is dried under vacuum. It has also been recrystallised twice from anhydrous *benzene immediately before use [Abuchowski et al. J Biol Chem 252 3582 1977]. [Beilstein 26 III/IV 66.]

General Description

A colorless crystalline solid with a pungent odor. Melting point 146°C. Density 1.32 g / cm3. Very slightly soluble in water. Toxic by ingestion and inhalation of vapors. Irritates skin and eyes. Used to make dyes.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Toxicity grading

Middle toxic

Uses

Cyanurchloride is an intermediate to manufacture of agrochemicals (triazine herbicides), dyestuffs, optical brighteners, tanning agents, reactive dyes, UV-absorbing agent, softening agents and pharmaceuticals, as well as block-builders for plastics. Product Data Sheet

Definition

ChEBI: A chloro-1,3,5-triazine in which the triazine ring is substituted on each carbon by chlorine. Its main use is in the preparation of the triazine-class pesticides.

Uses

Cyanuric Chloride is extensively used in the preparation of the triazine-class pesticides and herbicides. Cyanuric chloride is also used as a precursor to dyes and crosslinking agents due to the react ive chlorine atoms towards nucleophilic substitution reactions. Cyanuric chloride derivatives possess a large spectrum of activities as antibacterial and anticancer agents.

Extinguishing agent

carbon dioxide, dry powder,sandy soil

Flammability and hazard characteristics

When it contacts with water ,it emits toxic hydrogen chloride gas;when it is thermal it decomposes toxic hydrogen chloride gas

Chemical Properties

White Powder

Irritation data

skin-rabbit 500 mg/24 hours of moderate; Eyes-rabbit 0.05 mg/24 hours of severe

Uses

Reagent for the conversion of alcohols to chlorides and for the immobilization of microorganisms and enzymes.1

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Chemical Properties

Crystals Having a pungent odor. Soluble in chloroform, carbon tetrachloride, ethanol, hot ether, acetone, dioxane, slightly soluble in water.

Acute toxicity

Oral-rat LD50: 485 mg/kg; Oral-Mouse LD50: 350 mg/kg

Category

corrosive substances

Reactivity Profile

Cyanuric chloride reacts rapidly and exothermically with water to generate hydrogen chloride. A mixture with water in an industrial reactor with refrigeration turned off developed pressure that blew gaskets and filled the building with flammable vapors. An explosion occurred when the vapors were ignited [MCA Case History 1869(1972)]. Runaway reactions have occurred with acetone/water; methanol/water, ethoxyethanol/water, allyl alcohol/sodium hydroxide/water, 2-butanone/sodium hydroxide/water, and methanol/sodium bicarbonate [Loss Prev. Bull., 1979, (25), 21]. Reacts with methanol to give gaseous methyl chloride. Reacts rapidly with bicarbonates to generate gaseous carbon dioxide. Reacts vigorously with dimethyl formamide (DMF) to form carbon dioxide after a deceptive induction period [BCISC Quart. Safety Summ., 1960, 35, 24]. Can react with reducing agents to generate heat and products that may be gaseous (causing pressurization of closed containers). The products may themselves be capable of further reactions (such as combustion in the air).

Outline

Cyanuric chloride, white crystals with a strong irritant chlorine odor , is corrosive to the skin, having eye irritation and tearing property. Melting point 145 ℃, boiling point 190 ℃, UVλmax241nm (ethanol).it is Soluble in ethanol, ethyl ether, chloroform, acetic acid and acrylonitrile, insoluble in cold water. cooling of reaction of Cyanuric chloride and water is slow, when it is heated it is rapidly hydrolyzed to cyanuric acid (C3H3O3N3) and hydrochloric acid, the product are relatively soluble in water, so you can use the extraction method of separating. It Reacts With concentrated nitric acid and concentrated sulfuric acid at room temperature to be partial conversion of cyanuric acid, and it reacts with the sodium alkoxide to generate cyanuric acid triester, and it can also react with ammonia, amines, phenols and so on.
In recent years, there is rapid growth in consumption of cyanuric chloride in China, from 1998 to 2004 the average annual growth rate of Apparent consumption was about 32.2% ,in 2005, cyanuric chloride demand reached 50,000 tons, according to forecasts, from 2007 to 2012 cyanuric chloride will continue rapid growth in average rate of 6.0% , the market is very promising. Since cyanuric chloride subsequent products are enormous , the market demand is large, national research institutions and related businesses have continued to develop its downstream products, and open cyanuric chloride applications. Therefore, the new product by the cyanuric chloride derivatives are emerging, the market demand will be further expanded.
Related cyanuric chloride chemical reactions involving:
After 2-amino-4-nitrophenol diazotization, and H acid coupling, and chromium, cobalt complex post-processing,it is first condensed with cyanuric chloride ,then after condensation with ammonia to get Reactive Black K-BR. It is Mainly used for cotton, polyester/cotton printing.
With cyanuric chloride as raw materials, in trichlorethylene solution at 20~30 ℃, with the amine reaction , 2,4-dichloro-6-ethyl-1,3,5-triazine is produced, and then it reacts with ammonia to produce 2-amino-4-chloro-6-ethylamino triazine, and then it reacts with 2-chloro-2-methyl propionitrile , which can generate selective herbicides cyanazine for control annual or perennial narrow leaves or broadleaf weeds in corn field.

Uses

cyanuric chloride is an important fine chemical product, with a wide range of uses, it is the intermediate in pesticide industry, and the manufacture of reactive dyes raw material, it can used as all kinds of organic industrial production additives, such as fluorescent brighteners , textiles shrink-proof agents, surface active agents, it is one of the materials used in the manufacture of defense explosives and rubber accelerator and it is also the material for the synthesis of drugs by the pesticide and pharmaceutical industry.
The above information is edited by the chemicalbook of Tian Ye.

Air & Water Reactions

Reacts exothermically with water, especially if catalyzed or heated, to generate fumes of hydrochloric acid. Very slightly soluble in water.

Uses

Cyanurchloride is an intermediate to manufacture of agrochemicals, dyestuffs, optical brighteners, tanning agents, softening agents and pharmaceuticals, as well as block-builders for plastics.

Uses

Intermediate in the synthesis of active dyes, agricultural products, and drug substances. Reagent in organic synthesis. Coupling agent for nucleic acids and proteins; cyanuric chloride-activated paper is used in capillary and electroblotting applications, dot tests, and hybridization protocols.
InChI:InChI=1/C3H2Cl3N3/c4-2-1-3(5)8-9(6)7-2/h1,7H

108-77-0 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Aldrich (690740)  Cyanuricchloride  Lonza quality, ≥99.5% (w/w) 108-77-0 690740-25KG 4,967.82CNY Detail
Aldrich (690740)  Cyanuricchloride  Lonza quality, ≥99.5% (w/w) 108-77-0 690740-500G 607.23CNY Detail
Aldrich (C95501)  Cyanuricchloride  99% 108-77-0 C95501-1KG 592.02CNY Detail
Aldrich (C95501)  Cyanuricchloride  99% 108-77-0 C95501-250G 173.16CNY Detail
Aldrich (C95501)  Cyanuricchloride  99% 108-77-0 C95501-5G 145.08CNY Detail
Alfa Aesar (L03442)  Cyanuric chloride, 98%    108-77-0 1000g 306.0CNY Detail
Alfa Aesar (L03442)  Cyanuric chloride, 98%    108-77-0 250g 94.0CNY Detail
Alfa Aesar (L03442)  Cyanuric chloride, 98%    108-77-0 50g 59.0CNY Detail
TCI America (C0460)  Cyanuric Chloride  >98.0%(T) 108-77-0 500g 230.00CNY Detail
TCI America (C0460)  Cyanuric Chloride  >98.0%(T) 108-77-0 25g 110.00CNY Detail

108-77-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name cyanuric chloride

1.2 Other means of identification

Product number -
Other names CYANURIC CHLORIDE FOR SYNTHESIS

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Dyes,Finishing agents,Intermediates,Oxidizing/reducing agents,Photosensitive chemicals
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:108-77-0 SDS

108-77-0Synthetic route

2,4,6-tris(phenylthio)-1,3,5-triazine
30863-82-2

2,4,6-tris(phenylthio)-1,3,5-triazine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chlorine In dichloromethane at -45℃; under 2 Torr; Chlorination; Irradiation;100%
isocyanuric acid
108-80-5

isocyanuric acid

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With N,N-diethylaniline; trichlorophosphate for 3h; Heating;90%
With phosphorus pentachloride
With phosphorus pentachloride; trichlorophosphate
cyameluric acid tripotassium salt

cyameluric acid tripotassium salt

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With phosphorus pentachloride; trichlorophosphate at 110℃; for 6h; Inert atmosphere;77%
1,3,5-Triazine
290-87-9

1,3,5-Triazine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chlorine In tetrachloromethane byproducts: 2,4-dichloro-1,3,5-triazin; 200°C, 7 h;25%
1,3,5-Triazine
290-87-9

1,3,5-Triazine

A

2,4-dichloro-1,3,5-triazine
2831-66-5

2,4-dichloro-1,3,5-triazine

B

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chlorine In tetrachloromethane in closed tube at 140-200°C;A 4%
B 25%
With Cl2 In tetrachloromethane
methyl thiocyanate
556-64-9

methyl thiocyanate

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chlorine im Sonnenlicht;
hydrogen cyanide
74-90-8

hydrogen cyanide

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chlorine im Sonnenlicht;
With diethyl ether; chlorine
With chloroform; chlorine
potassium thioacyanate
333-20-0

potassium thioacyanate

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chlorine
cyanogen chloride
506-77-4

cyanogen chloride

A

2,4-dichloro-1,3,5-triazine
2831-66-5

2,4-dichloro-1,3,5-triazine

B

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With hydrogenchloride; hydrogen cyanide
cyanogen chloride
506-77-4

cyanogen chloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
at 280 - 300℃; durch Trimerisierung;
With alkaline earth chlorides; pyrographite at 200 - 500℃; durch Trimerisierung;
With pyrographite durch Trimerisierung;
chlorosulfenyl isocyanide dichloride
15999-70-9

chlorosulfenyl isocyanide dichloride

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

diethyl phosphorochloridothioate
2524-04-1

diethyl phosphorochloridothioate

Conditions
ConditionsYield
With O,O-Diethyl hydrogen phosphorodithioate In diethyl ether for 96h;
carbonyl diisothiocyanate
6470-09-3

carbonyl diisothiocyanate

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

N-chlorocarbonyl-carbonimidic acid dichloride
26551-86-0

N-chlorocarbonyl-carbonimidic acid dichloride

Conditions
ConditionsYield
With chlorine; iodine; iron(III) chloride; tin(IV) chloride at 60℃; Product distribution;
O,O-Diethyl hydrogen phosphorodithioate
298-06-6

O,O-Diethyl hydrogen phosphorodithioate

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

diethyl phosphorochloridothioate
2524-04-1

diethyl phosphorochloridothioate

Conditions
ConditionsYield
With chlorosulfinyl isocyanide In diethyl ether for 96h;
1,3,5-Trichlor-1λ4,3λ4,2,4,6-dithiatriazin
152172-19-5

1,3,5-Trichlor-1λ4,3λ4,2,4,6-dithiatriazin

cyanogen chloride
506-77-4

cyanogen chloride

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

1,3,5-Trichlor-1λ4,2,4,6-thiatriazin
58589-34-7

1,3,5-Trichlor-1λ4,2,4,6-thiatriazin

C

(1E,2E,4E,6E)-1,3,5,7-Tetrachloro-1λ4-[1,2,4,6,8]thiatetrazocine

(1E,2E,4E,6E)-1,3,5,7-Tetrachloro-1λ4-[1,2,4,6,8]thiatetrazocine

D

(1E,3E,5E,7E)-1,3,5,7-Tetrachloro-1λ4,3λ4-[1,3,2,4,6,8]dithiatetrazocine

(1E,3E,5E,7E)-1,3,5,7-Tetrachloro-1λ4,3λ4-[1,3,2,4,6,8]dithiatetrazocine

O,O-diisopropyl hydrogen phosphorodithioate
107-56-2

O,O-diisopropyl hydrogen phosphorodithioate

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

O,O-diisopropyl chlorothiophosphate
2524-06-3

O,O-diisopropyl chlorothiophosphate

Conditions
ConditionsYield
With chlorosulfinyl isocyanide In diethyl ether for 96h;
ammelide
645-93-2

ammelide

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

cyanuric acid
108-80-5

cyanuric acid

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2,4,6-triethoxy-[1,3,5]triazine
884-43-5

2,4,6-triethoxy-[1,3,5]triazine

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

tetrachloromethane
56-23-5

tetrachloromethane

2,4,6-tricyano-1,3,5-triazine
7615-57-8

2,4,6-tricyano-1,3,5-triazine

iodine
7553-56-2

iodine

chlorine
7782-50-5

chlorine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

thiocyanato

thiocyanato

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
With chloroform; chlorine; iron(III) chloride
1,3,5-Triazine
290-87-9

1,3,5-Triazine

tetrachloromethane
56-23-5

tetrachloromethane

chlorine
7782-50-5

chlorine

A

2,4-dichloro-1,3,5-triazine
2831-66-5

2,4-dichloro-1,3,5-triazine

B

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
at 200℃;
phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

2,4,6-trimethoxy-1,3,5-triazine
877-89-4

2,4,6-trimethoxy-1,3,5-triazine

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

methylene chloride
74-87-3

methylene chloride

Conditions
ConditionsYield
at 200℃;
methyl thiocyanate
556-64-9

methyl thiocyanate

chlorine
7782-50-5

chlorine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
namentlich an der Sonne;
hydrogenchloride
7647-01-0

hydrogenchloride

cyanogen chloride
506-77-4

cyanogen chloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

water
7732-18-5

water

cyanogen chloride
506-77-4

cyanogen chloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

chlorine
7782-50-5

chlorine

cyanogen chloride
506-77-4

cyanogen chloride

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

hydrogenchloride
7647-01-0

hydrogenchloride

cyanogen chloride
506-77-4

cyanogen chloride

hydrogen cyanide (0.5 mol)

hydrogen cyanide (0.5 mol)

A

2,4-dichloro-1,3,5-triazine
2831-66-5

2,4-dichloro-1,3,5-triazine

B

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Conditions
ConditionsYield
at 65℃;
aluminium trichloride
7446-70-0

aluminium trichloride

cyanogen chloride
506-77-4

cyanogen chloride

benzene
71-43-2

benzene

A

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

B

benzonitrile
100-47-0

benzonitrile

phenyl thiocyanate
5285-87-0

phenyl thiocyanate

chlorine
7782-50-5

chlorine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

morpholine
110-91-8

morpholine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2,6-Dichloro-4-morpholino-1,3,5-triazine
6601-22-5

2,6-Dichloro-4-morpholino-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at -78℃; for 0.166667h;100%
With triethylamine In dichloromethane at -78 - -30℃; for 1.5h; Inert atmosphere;99%
With triethylamine In acetone for 0.5h; Cooling with ice;98%
morpholine
110-91-8

morpholine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2-chloro-4,6-di-morpholin-4-yl-[1,3,5]triazine
7597-22-0

2-chloro-4,6-di-morpholin-4-yl-[1,3,5]triazine

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane at 0 - 40℃; for 3h;100%
In dichloromethane; water at 0 - 5℃; for 3.25h; Large scale;98%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 1h;95%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

tert-butyl 4-(4,6-dichloro-1,3,5-triazin-2-yl)piperazine-1-carboxylate
271592-49-5

tert-butyl 4-(4,6-dichloro-1,3,5-triazin-2-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.5h;100%
With sodium hydrogencarbonate In acetone at 0℃; for 2h;96%
With sodium hydrogencarbonate In acetone Condensation;93%
hexenylmagnesium bromide
32359-01-6

hexenylmagnesium bromide

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2-(hex-1'-ynyl)-4,6-dichloro-1,3,5-triazine
14894-35-0

2-(hex-1'-ynyl)-4,6-dichloro-1,3,5-triazine

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether at 25℃; for 3h; alkynylation;100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

(3,3-dimethylbut-1-yn-1-yl)magnesium bromide
104480-60-6

(3,3-dimethylbut-1-yn-1-yl)magnesium bromide

2-(3',3'-dimethylbutyn-1'-yl)-4,6-dichloro-1,3,5-triazine
112749-18-5

2-(3',3'-dimethylbutyn-1'-yl)-4,6-dichloro-1,3,5-triazine

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether at 25℃; for 15h; alkynylation;100%
In tetrahydrofuran; diethyl ether at 5℃;
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

(3-aminophenyl)carbamic acid tert-butyl ester
68621-88-5

(3-aminophenyl)carbamic acid tert-butyl ester

2-([3-tert-butoxycarbonylaminophenyl]amino)-4,6-dichloro[1,3,5]triazine
537049-05-1

2-([3-tert-butoxycarbonylaminophenyl]amino)-4,6-dichloro[1,3,5]triazine

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetone at 0℃; pH=7 - 8;100%
Stage #1: 1,3,5-trichloro-2,4,6-triazine; (3-aminophenyl)carbamic acid tert-butyl ester In acetone at 0℃;
Stage #2: With sodium hydrogencarbonate In water; acetone pH=1 - 7;
99%
Stage #1: 1,3,5-trichloro-2,4,6-triazine; (3-aminophenyl)carbamic acid tert-butyl ester In water; acetone at -10 - 20℃; for 3h; pH=2;
Stage #2: With sodium hydrogencarbonate In water; acetone for 0.5h; pH=8;
99.6%
With sodium hydrogencarbonate In water; acetone at 0℃;85%
With sodium hydrogencarbonate
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

cyclohexylamine
108-91-8

cyclohexylamine

6-cyclohexylamino-2,4-dichloro-1,3,5-triazine
27282-86-6

6-cyclohexylamino-2,4-dichloro-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 2h;100%
With sodium carbonate In 1,4-dioxane; dichloromethane; water90%
In diethyl ether at -15 - -10℃;81%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2‐chlorotrityl chloride resin

2‐chlorotrityl chloride resin

resin A

resin A

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; 2‐chlorotrityl chloride resin In tetrahydrofuran at 20℃; for 0.25h; Wang resin;
Stage #2: With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 18h;
100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

(2S,3aS,7aS)-tert-butyl 2-carbamoyloctahydro-1H-indole-1-carboxylate
115238-27-2

(2S,3aS,7aS)-tert-butyl 2-carbamoyloctahydro-1H-indole-1-carboxylate

(2S,3aS,7aS)-2-cyano-octahydro-indole-1-carboxylic acid 1-tert-butyl ester
781676-42-4

(2S,3aS,7aS)-2-cyano-octahydro-indole-1-carboxylic acid 1-tert-butyl ester

Conditions
ConditionsYield
In DMF (N,N-dimethyl-formamide) at 0 - 20℃; for 6h;100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

1H,1H,2H,2H-Perfluorodecanethiol
34143-74-3

1H,1H,2H,2H-Perfluorodecanethiol

2-chloro-4,6-bis(1H,1H,2H,2H-perfluorodecylthio)-1,3,5-triazine

2-chloro-4,6-bis(1H,1H,2H,2H-perfluorodecylthio)-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0℃;100%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 1 - 2℃; for 2.5h; Inert atmosphere; Schlenk technique;91%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

1-dodecylthiol
112-55-0

1-dodecylthiol

2-chloro-4,6-bis(dodecylthio)-1,3,5-triazine
1041173-47-0

2-chloro-4,6-bis(dodecylthio)-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 1 - 2℃; for 2.5h; Inert atmosphere; Schlenk technique;83%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

1H,1H,2H,2H-Perfluorodecanethiol
34143-74-3

1H,1H,2H,2H-Perfluorodecanethiol

2,4-dichloro-6-(1H,1H,2H,2H-perfluorodecylthio)-1,3,5-triazine
916667-82-8

2,4-dichloro-6-(1H,1H,2H,2H-perfluorodecylthio)-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

1-dodecylthiol
112-55-0

1-dodecylthiol

2,4-dichloro-6-(dodecylthio)-1,3,5-triazine
75951-06-3

2,4-dichloro-6-(dodecylthio)-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

allyl alcohol
107-18-6

allyl alcohol

2-allyloxy-4,6-dichloro-1,3,5-triazine
26650-76-0

2-allyloxy-4,6-dichloro-1,3,5-triazine

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 10℃; for 0.25h;100%
With 2,4,6-trimethyl-pyridine In acetone for 1h; Cooling with ice;61%
With N-ethyl-N,N-diisopropylamine In dichloromethane at -10 - 20℃; for 24h;
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

tert-butyl 4-(aminocarbonyl)-4-isopropylpiperidine-1-carboxylate
1093396-56-5

tert-butyl 4-(aminocarbonyl)-4-isopropylpiperidine-1-carboxylate

tert-butyl 4-cyano-4-isopropylpiperidine-1-carboxylate
1093396-58-7

tert-butyl 4-cyano-4-isopropylpiperidine-1-carboxylate

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃;100%
isonipecotic acid
498-94-2

isonipecotic acid

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

methylamine
74-89-5

methylamine

1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-4-piperidinecarboxylicacid
1141894-74-7

1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-4-piperidinecarboxylicacid

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; methylamine With sodium hydroxide In water; acetonitrile at 0℃; for 0.5h; pH=9 - 10;
Stage #2: isonipecotic acid In water; acetonitrile at 0 - 20℃; for 1h; pH=9 - 10;
100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

3-(diethoxy-methyl-silanyl)-propylamine
3179-76-8

3-(diethoxy-methyl-silanyl)-propylamine

6-(3-dietoxymethylsilylpropyl)amino-1,3,5-triazine-2,4-dichloride

6-(3-dietoxymethylsilylpropyl)amino-1,3,5-triazine-2,4-dichloride

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at -10℃; for 2h; Inert atmosphere;100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

1-(4-fluorophenyl)piperazine dihydrochloride
64090-19-3

1-(4-fluorophenyl)piperazine dihydrochloride

2,4-dichloro-6-[4-(4-fluorophenyl)piperazin-1-yl]-1,3,5-triazine

2,4-dichloro-6-[4-(4-fluorophenyl)piperazin-1-yl]-1,3,5-triazine

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine With sodium carbonate In tetrahydrofuran at 0℃; for 0.0833333h;
Stage #2: 1-(4-fluorophenyl)piperazine dihydrochloride In tetrahydrofuran at 20℃; for 72h;
100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Pd(II)-5-(3-aminophenyl)-10,15,20-tris(4-methylphenyl)porphyrin

Pd(II)-5-(3-aminophenyl)-10,15,20-tris(4-methylphenyl)porphyrin

Pd(II)-5-[3-amino(triazine-2,4-dichloride)phenyl]-10,15,20-tris(4-methylphenyl)porphyrin

Pd(II)-5-[3-amino(triazine-2,4-dichloride)phenyl]-10,15,20-tris(4-methylphenyl)porphyrin

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; Pd(II)-5-(3-aminophenyl)-10,15,20-tris(4-methylphenyl)porphyrin In tetrahydrofuran at 0℃; for 2h; Inert atmosphere;
Stage #2: With potassium carbonate In tetrahydrofuran; water for 3h; Inert atmosphere;
100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

9-(mercapto)-1,7-dicarba-closo-dodecaborane(12)
64493-44-3

9-(mercapto)-1,7-dicarba-closo-dodecaborane(12)

2-chloro-4,6-bis(1,7-dicarba-closo-dodeca-boran-9-ylthio)-1,3,5-triazine

2-chloro-4,6-bis(1,7-dicarba-closo-dodeca-boran-9-ylthio)-1,3,5-triazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 0 - 20℃; Reflux;100%
With N-ethyl-N,N-diisopropylamine In acetonitrile at 0℃; for 5.33333h; Reflux; Schlenk technique; Inert atmosphere;100%
With N-ethyl-N,N-diisopropylamine In acetonitrile at 0℃; Inert atmosphere; Reflux;100%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2,2'-iminobis[ethanol]
111-42-2

2,2'-iminobis[ethanol]

2,2',2'',2''',2'''',2'''''-((1,3,5-triazine-2,4,6-triyl)tris(azanetriyl))hexaethanol
4403-08-1

2,2',2'',2''',2'''',2'''''-((1,3,5-triazine-2,4,6-triyl)tris(azanetriyl))hexaethanol

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; 2,2'-iminobis[ethanol] In tetrahydrofuran at 20℃; for 1h;
Stage #2: With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20 - 85℃; for 17h;
99%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20 - 85℃; for 18h;99%
With potassium carbonate In tetrahydrofuran at 0 - 20℃; for 26h; Reflux;58.6%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

4,6-dichloro-1,3,5-triazin-2-amine
933-20-0

4,6-dichloro-1,3,5-triazin-2-amine

Conditions
ConditionsYield
With ammonium hydroxide In dichloromethane at 22 - 26℃;99%
With ammonium hydroxide In water; acetone at 0 - 5℃; for 0.5h;95%
With ammonia In water; acetone at 0℃; Heating;93%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

Propargylamine
2450-71-7

Propargylamine

N2,N4,N6-tri(prop-2-yn-1-yl)-1,3,5-triazine-2,4,6-triamine
144535-20-6

N2,N4,N6-tri(prop-2-yn-1-yl)-1,3,5-triazine-2,4,6-triamine

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran; methanol at 0℃; for 2.5h; Reflux;99%
In toluene for 20h; Reflux;42%
In toluene for 3h; Heating;32%
In toluene
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

n-dioctylamine
1120-48-5

n-dioctylamine

2-chloro-4,6-bis-(di-n-octylamino)-s-triazine
165612-58-8

2-chloro-4,6-bis-(di-n-octylamino)-s-triazine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 25h; Cooling with ice;99%
With triethylamine In dichloromethane at 20℃; for 24h;97%
With triethylamine In dichloromethane at 25℃; for 24h;97%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

dibenzylamine
103-49-1

dibenzylamine

2-(N,N-dibenzylamino)-4,6-dichloro-1,3,5-triazine
47301-29-1

2-(N,N-dibenzylamino)-4,6-dichloro-1,3,5-triazine

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 1h;99%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 3h; Inert atmosphere;67%
Substitution; Amination;
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0℃; for 2h;
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃;
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

4-tert-Butylaniline
769-92-6

4-tert-Butylaniline

4-amino-6-chloro-2-(4'-tert-butylanilino)-1,3,5-triazine
361523-39-9

4-amino-6-chloro-2-(4'-tert-butylanilino)-1,3,5-triazine

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; 4-tert-Butylaniline With N-ethyl-N,N-diisopropylamine In tetrahydrofuran for 2h;
Stage #2: With ammonia In tetrahydrofuran at 20℃; for 2.5h; Further stages.;
99%
piperidine
110-89-4

piperidine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

4-methoxy-benzylamine
2393-23-9

4-methoxy-benzylamine

N-(4-methoxybenzyl)-4,6-di(piperidinyl)-1,3,5-triazin-2-amine

N-(4-methoxybenzyl)-4,6-di(piperidinyl)-1,3,5-triazin-2-amine

Conditions
ConditionsYield
Stage #1: 1,3,5-trichloro-2,4,6-triazine; 4-methoxy-benzylamine With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 3h;
Stage #2: piperidine In tetrahydrofuran at 20℃; for 15h;
99%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

bis(2-tert-butyloxycarbonylaminoethyl)amine
117499-16-8

bis(2-tert-butyloxycarbonylaminoethyl)amine

{2-[{4-[bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-6-chloro-[1,3,5]triazin-2-yl}-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
893842-35-8

{2-[{4-[bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-6-chloro-[1,3,5]triazin-2-yl}-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃;99%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 16h;99%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 12 - 12.5h; Product distribution / selectivity;99%
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

cyclohexylmethyl alcohol
100-49-2

cyclohexylmethyl alcohol

2,4-dichloro-6-cyclohexylmethoxy-[1,3,5]triazine
502767-34-2

2,4-dichloro-6-cyclohexylmethoxy-[1,3,5]triazine

Conditions
ConditionsYield
With potassium hydrogencarbonate In toluene99%
With potassium hydrogencarbonate; 18-crown-6 ether In toluene99%
With potassium carbonate; 18-crown-6 ether In toluene for 18h; Heating / reflux;99%
With potassium hydrogencarbonate; 18-crown-6 ether In toluene for 18h; Heating / reflux;
With potassium hydrogencarbonate; 18-crown-6 ether In toluene for 18h; Heating / reflux;

108-77-0Related news

Original articleMultifunctionalization of Cyanuric chloride (cas 108-77-0) for the stepwise synthesis of potential multimodal imaging chemical entities08/19/2019

We report a synthetic strategy to combine different moieties in a single structure using cyanuric chloride (2,4,6-trichlorotriazine) as a starting platform for preparing potential bioimaging agents. This reacted with macrocycles of the porphyrin family and DOTA type metal chelators through mono-...detailed

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields