4-Methoxy-3-(propan-2-yl)benzoic acid

Base Information

• Chemical Name: 4-Methoxy-3-(propan-2-yl)benzoic acid
• CAS No.: 33537-78-9
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• European Community (EC) Number: 855-996-7
• Mol file: 33537-78-9.mol

Synonyms:4-Methoxy-3-isopropylbenzoic acid;33537-78-9;4-methoxy-3-(propan-2-yl)benzoic acid;4-methoxy-3-propan-2-ylbenzoic acid;3-isopropyl-4-methoxybenzoic acid;SCHEMBL4695867;4-Methoxy-3-isopropylbenzoicacid;PQDZTSSEWJIYOO-UHFFFAOYSA-N;GS2774;MFCD16303871;AKOS013201795;CS-0196026;E91123;EN300-122839;Z1171157997

Chemical Property of 4-Methoxy-3-(propan-2-yl)benzoic acid

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 201

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1=C(C=CC(=C1)C(=O)O)OC

Technology Process of 4-Methoxy-3-(propan-2-yl)benzoic acid

There total 5 articles about 4-Methoxy-3-(propan-2-yl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-isopropyl-4-methoxy-benzoic acid methyl ester (105401-95-4) → 4-Methoxy-3-isopropylbenzoic acid (33537-78-9)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01337a053

Reference yield:

4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid (94112-85-3) → 4-Methoxy-3-isopropylbenzoic acid (33537-78-9)

Guidance literature:

With sodium hypochlorite;

Reference yield:

4-(4-hydroxy-3-isopropyl-phenyl)-4-oxo-butyric acid (106165-94-0) → 4-Methoxy-3-isopropylbenzoic acid (33537-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous KOH

2: aqueous NaClO

With potassium hydroxide; sodium hypochlorite;

upstream raw materials:

4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid

3-isopropyl-4-methoxy-benzoic acid methyl ester

4-(4-hydroxy-3-isopropyl-phenyl)-4-oxo-butyric acid

1-bromo-4-methoxy-benzene

Downstream raw materials:

4-hydroxy-3-isopropyl-benzoic acid methyl ester

C₂₁H₃₂O₃

(+/-)-Hinokiol methyl ether

1,2-di-(4-Methoxy-3-isopropylphenyl)ethane