2,2'-BITHIOPHENE-5-CARBOXYLIC ACID

Base Information

• Chemical Name: 2,2'-BITHIOPHENE-5-CARBOXYLIC ACID
• CAS No.: 2060-55-1
• Molecular Formula: C9H6 O2 S2
• Molecular Weight: 210.277
• Hs Code.: 2934999090
• Mol file: 2060-55-1.mol

Synonyms:5-(2-Thiophenyl)-2-thiophenecarboxylicacid; [2,2'-Bithiophenyl]-5-carboxylic acid

Chemical Property of 2,2'-BITHIOPHENE-5-CARBOXYLIC ACID

Chemical Property:

• Melting Point: 183-184 °C
• Boiling Point: 396.1°Cat760mmHg
• PKA: 3.54±0.10(Predicted)
• Flash Point: 193.4°C
• PSA: 93.78000
• Density: 1.438g/cm³
• LogP: 3.17480

Purity/Quality:

97% ^*data from raw suppliers

2,2''-Bithiophene-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-BITHIOPHENE-5-CARBOXYLIC ACID

There total 11 articles about 2,2'-BITHIOPHENE-5-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

carbon dioxide (124-38-9,18923-20-1) + 2,2'-Bithiophene (492-97-7) → 5-(thien-2-yl)thiophene-2-carboxylic acid (2060-55-1)

Guidance literature:

2,2'-Bithiophene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

carbon dioxide; In tetrahydrofuran; at -78 ℃; Further stages.;

DOI:10.1021/ja994231l

Reference yield: 72.0%

(2Z,4E)-2-((1Z,3E)-1-Carboxy-4-thiophen-2-yl-buta-1,3-dienyldisulfanyl)-5-thiophen-2-yl-penta-2,4-dienoic acid (116016-58-1) → 5-(thien-2-yl)thiophene-2-carboxylic acid (2060-55-1)

Guidance literature:

With iodine; In 1,2-dimethoxyethane; for 3h; Heating;

Reference yield: 67.0%

→ 5-(thien-2-yl)thiophene-2-carboxylic acid (2060-55-1)

Guidance literature:

upstream raw materials:

(2Z,4E)-2-((1Z,3E)-1-Carboxy-4-thiophen-2-yl-buta-1,3-dienyldisulfanyl)-5-thiophen-2-yl-penta-2,4-dienoic acid

2-methyl-2,5'-bithiophene

2,2'-bithiophene-5-carboxaldehyde

carbon dioxide

Downstream raw materials:

C₂₆H₁₈O₄S₄

trans-(molybdenum)2(2,4,6-triisopropylbenzoate)2(OOC(2,4-thiophene)2H)

trans-(tungsten)2(2,4,6-triisopropylbenzoate)2(OOC(2,4-thiophene)2H)

5'''''''-Bromo-4'',4'''''-dioctyl-[2,2';5',2'';5'',2''';5''',2'''';5'''',2''''';5''''',2'''''';5'''''',2''''''']octithiophene-5-carboxylic acid benzyl ester