16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol

Base Information

Chemical Name:16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol
CAS No.:472-57-1
Molecular Formula:C18H22 O2
Molecular Weight:270.371
Hs Code.:
Mol file:472-57-1.mol

Synonyms:Estra-1,3,5(10)-trien-3-ol,16b,17b-epoxy- (7CI,8CI);16,17-Epoxy-1H-cyclopenta[a]phenanthrene, estra-1,3,5(10)-trien-3-ol deriv.

Suppliers and Price of 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol

Chemical Property:

Vapor Pressure:4.96E-08mmHg at 25°C
Boiling Point:430.9°Cat760mmHg
Flash Point:198.2°C
PSA：32.76000
Density:1.199g/cm³
LogP:3.62560

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol

There total 4 articles about 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1239-35-6
16α-bromo-3-hydroxy-1,3,5(10)-estratrien-17-one 3-acetate

: 472-57-1
3-Hydroxyestra-1,3,5(10)-triene 16β,17β-Oxide

Guidance literature:: With lithium aluminium tetrahydride; diethyl ether; Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge;
DOI:10.1021/jo01102a028

Reference yield:

: 20592-42-1
estra-1,3,5⁽¹⁰⁾,16-tetraene-3,17-diol diacetate

: 472-57-1
3-Hydroxyestra-1,3,5(10)-triene 16β,17β-Oxide

Guidance literature:: Multi-step reaction with 2 steps

1: bromine

2: lithium alanate; diethyl ether / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge

With lithium aluminium tetrahydride; diethyl ether; bromine;
DOI:10.1021/jo01102a028