1,1'-[2-Chloro-2-(4-methoxyphenyl)ethene-1,1-diyl]dibenzene

Base Information

• Chemical Name: 1,1'-[2-Chloro-2-(4-methoxyphenyl)ethene-1,1-diyl]dibenzene
• CAS No.: 33686-66-7
• Molecular Formula: C21H17ClO
• Molecular Weight: 320.818
• DSSTox Substance ID: DTXSID30538104
• Nikkaji Number: J1.014.231H
• Mol file: 33686-66-7.mol

Synonyms:33686-66-7;DTXSID30538104;1,1'-[2-Chloro-2-(4-methoxyphenyl)ethene-1,1-diyl]dibenzene

Chemical Property of 1,1'-[2-Chloro-2-(4-methoxyphenyl)ethene-1,1-diyl]dibenzene

Chemical Property:

• XLogP3: 6.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 320.0967929
• Heavy Atom Count: 23
• Complexity: 363

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=CC=C3)Cl

Technology Process of 1,1'-[2-Chloro-2-(4-methoxyphenyl)ethene-1,1-diyl]dibenzene

There total 5 articles about 1,1'-[2-Chloro-2-(4-methoxyphenyl)ethene-1,1-diyl]dibenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

benzophenone (119-61-9) + 2-[Chloro-(4-methoxy-phenyl)-methyl]-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide (188840-56-4) → 4-(1-chloro-2,2-diphenyl-vinyl)-anisole (33686-66-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 20h; Heating;

DOI:10.1016/S0040-4020(98)00886-2

Reference yield:

1-(4-methoxyphenyl)-2,2-diphenylethanone (1889-74-3) → 4-(1-chloro-2,2-diphenyl-vinyl)-anisole (33686-66-7)

Guidance literature:

With phosphorus pentachloride; benzene;

DOI:10.1021/ja01611a093

Reference yield:

2-bromo-1-(4-methoxy-phenyl)-2-phenyl-ethanone (1889-77-6) → 4-(1-chloro-2,2-diphenyl-vinyl)-anisole (33686-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; AlCl₃

2: benzene; PCl₅

With aluminium trichloride; phosphorus pentachloride; benzene;

DOI:10.1021/ja01611a093

upstream raw materials:

1-(4-methoxyphenyl)-2,2-diphenylethanone

2,2-diphenyl-1-(4-methoxyphenyl)ethylene

benzophenone

2-[Chloro-(4-methoxy-phenyl)-methyl]-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide