4-amino-N-quinolin-8-ylbenzenesulfonamide

Base Information

Chemical Name:4-amino-N-quinolin-8-ylbenzenesulfonamide
CAS No.:33757-63-0
Molecular Formula:C15H13N3O2S
Molecular Weight:299.353
Hs Code.:
DSSTox Substance ID:DTXSID90353698
Nikkaji Number:J646.386J
Wikidata:Q82131417
ChEMBL ID:CHEMBL3392455

Synonyms:4-amino-N-quinolin-8-ylbenzenesulfonamide;33757-63-0;Benzenesulfonamide, 4-amino-N-8-quinolinyl-;4-AMINO-N-(QUINOLIN-8-YL)BENZENESULFONAMIDE;4-amino-N-(quinolin-8-yl)benzene-1-sulfonamide;CBMicro_006446;Oprea1_154927;CHEMBL3392455;DTXSID90353698;SMSF0005860;MFCD02208554;AKOS000157923;CB08725;n-(8-quinolyl)-p-aminobenzenesulfonamide;NCGC00161693-01;LS-09627;BIM-0006535.P001;SR-01000402509;SR-01000402509-1

Suppliers and Price of 4-amino-N-quinolin-8-ylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-amino-N-quinolin-8-ylbenzenesulfonamide

Chemical Property:

Melting Point:193 °C(Solv: ethanol (64-17-5))
Boiling Point:545.9±56.0 °C(Predicted)
PSA：93.46000
Density:1.437±0.06 g/cm3(Predicted)
LogP:4.35280
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:299.07284784
Heavy Atom Count:21
Complexity:440

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)N)N=CC=C2

Technology Process of 4-amino-N-quinolin-8-ylbenzenesulfonamide

There total 9 articles about 4-amino-N-quinolin-8-ylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 16082-65-8
N-(4-(N-(quinolin-8-yl)sulfamoyl)phenyl)acetamide

: 33757-63-0
N-(quinolin-8-yl)-4-aminobenzenesulfonamide

Guidance literature:: With hydrogenchloride; water; In ethanol; at 100 ℃; for 1h;
DOI:10.3390/ijms19051482

Reference yield:

: 578-66-5
8-amino quinoline

: 33757-63-0
N-(quinolin-8-yl)-4-aminobenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 0 - 60 °C

2: 4.8 g / NaOH / H₂O / 2 h / Heating

With pyridine; sodium hydroxide; In water;
DOI:10.1021/ol062816w

Reference yield:

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 33757-63-0
N-(quinolin-8-yl)-4-aminobenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 0 - 60 °C

2: 4.8 g / NaOH / H₂O / 2 h / Heating

With pyridine; sodium hydroxide; In water;
DOI:10.1021/ol062816w