2-Chloro-N-[4-(3,4-dimethoxyphenyl)butyl]acetamide

Base Information

Chemical Name:2-Chloro-N-[4-(3,4-dimethoxyphenyl)butyl]acetamide
CAS No.:33760-10-0
Molecular Formula:C₁₄H₂₀ClNO₃
Molecular Weight:285.771
Hs Code.:
DSSTox Substance ID:DTXSID90507715
Wikidata:Q82364095

Synonyms:2-CHLORO-N-[4-(3,4-DIMETHOXYPHENYL)BUTYL]ACETAMIDE;33760-10-0;SCHEMBL3452625;DTXSID90507715

Suppliers and Price of 2-Chloro-N-[4-(3,4-dimethoxyphenyl)butyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Chloro-N-[4-(3,4-dimethoxyphenyl)butyl]acetamide

Chemical Property:

Melting Point:85-86 °C(Solv: hexane (110-54-3))
Boiling Point:466.5±45.0 °C(Predicted)
PSA：51.05000
Density:1.126±0.06 g/cm3(Predicted)
LogP:3.22180
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:285.1131712
Heavy Atom Count:19
Complexity:263

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCCCNC(=O)CCl)OC

Technology Process of 2-Chloro-N-[4-(3,4-dimethoxyphenyl)butyl]acetamide

There total 3 articles about 2-Chloro-N-[4-(3,4-dimethoxyphenyl)butyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 33760-10-0
N-Chloroacetyl-4-(3,4-dimethoxyphenyl)butylamine

Guidance literature:

Reference yield:

: 76356-14-4
4-(3,4-dimethoxyphenyl)butanamide

: 33760-10-0
N-Chloroacetyl-4-(3,4-dimethoxyphenyl)butylamine

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether; tetrahydrofuran / 1.5 h / Heating

2: Na₂CO₃ / CH₂Cl₂; H₂O / 0.5 h / Ambient temperature

With lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1248/cpb.29.128