2-Methylpyridine-4-carbothioamide

Base Information

Chemical Name:2-Methylpyridine-4-carbothioamide
CAS No.:3390-77-0
Molecular Formula:C7H8N2S
Molecular Weight:152.22
Hs Code.:2933399090
European Community (EC) Number:878-532-5
DSSTox Substance ID:DTXSID90388208
Mol file:3390-77-0.mol

Synonyms:2-methylpyridine-4-carbothioamide;3390-77-0;2-Methyl-4-pyridinecarbothioamide;2-Methylisonicotinic acid thioamide;2-Methy-4-Thioisonicotinicamide;2-methyl-4-thiocarbamoylpyridine;2-Methylthioisonicotinamide;Isonicotinamide, 2-methylthio-;SCHEMBL18375601;DTXSID90388208;WPZPVMMGTQFGJI-UHFFFAOYSA-N;2-Methyl-4-pyridinecarbothioamide #;2-Methyl-4-pyrridinethiocarbothiamide;CS-0237549;FT-0672283;EN300-1852795

Suppliers and Price of 2-Methylpyridine-4-carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methylthioisonicotinamide
1g
$ 1320.00

Medical Isotopes, Inc.
2-Methylthioisonicotinamide
1 g
$ 2200.00

Medical Isotopes, Inc.
2-Methylthioisonicotinamide
100 mg
$ 650.00

AK Scientific
2-Methyl-4-pyridinecarbothioamide
1g
$ 773.00

AK Scientific
2-Methyl-4-pyridinecarbothioamide
100mg
$ 289.00

Total 8 raw suppliers

Chemical Property of 2-Methylpyridine-4-carbothioamide

Chemical Property:

Melting Point:187 °C(Solv: methanol (67-56-1))
Boiling Point:288.3±42.0 °C(Predicted)
PKA:12.14±0.29(Predicted)
PSA：71.00000
Density:1.212±0.06 g/cm3(Predicted)
LogP:1.72450
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:152.04081944
Heavy Atom Count:10
Complexity:136

Purity/Quality:

95% ^*data from raw suppliers

2-Methylthioisonicotinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=CC(=C1)C(=S)N
Uses 2-Methylthioisonicotinamide is an impurity of Ethionamide (E890420) with tuberculostatic activity.

Technology Process of 2-Methylpyridine-4-carbothioamide

There total 4 articles about 2-Methylpyridine-4-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19354-04-2
2-methyl-isonicotinic acid amide

: 3390-77-0
2-methyl-thioisonicotinic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: P₂O₅ / 160 - 170 °C / 20 - 30 Torr

2: ethanol; tris-<2-hydroxy-ethyl>-amine / Einleiten von H₂S

With triethanolamine; ethanol; phosphorus pentoxide;

Reference yield:

: 2214-53-1
2-methyl-4-cyanopyridine

: 3390-77-0
2-methyl-thioisonicotinic acid amide

Guidance literature:: With triethanolamine; ethanol; Einleiten von H₂S;

Reference yield:

: 25635-17-0
ethyl 2-methylpyridine-4-carboxylate

: 3390-77-0
2-methyl-thioisonicotinic acid amide

Guidance literature:: Multi-step reaction with 3 steps

1: concentrated aqueous NH₃

2: P₂O₅ / 160 - 170 °C / 20 - 30 Torr

3: ethanol; tris-<2-hydroxy-ethyl>-amine / Einleiten von H₂S

With ammonium hydroxide; triethanolamine; ethanol; phosphorus pentoxide;