1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile

Base Information

Chemical Name:1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile
CAS No.:339094-26-7
Molecular Formula:C14H17NO2
Molecular Weight:231.294
Hs Code.:
DSSTox Substance ID:DTXSID40573041
Nikkaji Number:J1.521.565H
Wikidata:Q82461611

Synonyms:1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile;339094-26-7;1-(3,5-Dimethoxyphenyl)cyclopentane-1-carbonitrile;Cyclopentanecarbonitrile, 1-(3,5-dimethoxyphenyl)-;DTXSID40573041;AC5939;MFCD06657290;AKOS029465451;SY225723;A918963

Suppliers and Price of 1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:231.125928785
Heavy Atom Count:17
Complexity:289

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1)C2(CCCC2)C#N)OC

Technology Process of 1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile

There total 1 articles about 1-(3,5-Dimethoxyphenyl)cyclopentanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 110-52-1
1,4-dibromo-butane

: 13388-75-5
3,5-dimethoxyphenylacetonitrile

: 339094-26-7
1-(3,5-dimethoxyphenyl)cyclopentane-1-carbonitrile

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; at 0 - 20 ℃; for 0.0833333h;
DOI:10.1021/acs.jmedchem.0c02053

Reference yield: 87.0%

: 339094-26-7
1-(3,5-dimethoxyphenyl)cyclopentane-1-carbonitrile

: 339094-30-3
1-(3,5-dimethoxyphenyl)cyclopentane-1-carbaldehyde

Guidance literature:: 1-(3,5-dimethoxyphenyl)cyclopentane-1-carbonitrile; With diisobutylaluminium hydride; In dichloromethane; at -78 ℃;

With Rochelle's salt;
DOI:10.1246/cl.2001.192

Reference yield:

: 339094-26-7
1-(3,5-dimethoxyphenyl)cyclopentane-1-carbonitrile

: 951039-74-0
3,5-dimethoxy-1-(1-heptylcyclopentyl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1.1: 87 percent / diisobutylaluminum hydride / CH₂Cl₂ / -78 °C

2.1: bis(trimethylsilyl)amide / tetrahydrofuran / 0 - 10 °C

2.2: 80 percent / tetrahydrofuran / 0.75 h / 10 °C

3.1: 98 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

With hydrogen; hexamethyldisilazide; diisobutylaluminium hydride; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm070121a