2-Bromo-1-(bromomethyl)-4-chlorobenzene

Base Information

• Chemical Name: 2-Bromo-1-(bromomethyl)-4-chlorobenzene
• CAS No.: 33924-45-7
• Molecular Formula: C7H5Br2Cl
• Molecular Weight: 284.378
• Hs Code.: 2903999090
• European Community (EC) Number: 848-741-6
• Mol file: 33924-45-7.mol

Synonyms:33924-45-7;2-bromo-1-(bromomethyl)-4-chlorobenzene;2-Bromo-4-chlorobenzyl bromide;2-bromo-1-(bromomethyl)-4-chloro-benzene;MFCD12024978;2-Bromo-1-bromomethyl-4-chlorobenzene;Benzene, 2-bromo-1-(bromomethyl)-4-chloro-;2-Bromo-4-chlorobenzylbromide;SCHEMBL979069;KZIGUGMFQVNQFJ-UHFFFAOYSA-N;BBL103705;STL557515;AKOS015916865;2-bromo-1-bromomethyl-4-chloro-benzene;AS-19636;SY187385;CS-0060420;FT-0714184;EN300-76695;N10597

Chemical Property of 2-Bromo-1-(bromomethyl)-4-chlorobenzene

Chemical Property:

• Boiling Point: 138-142 °C(Press: 12 Torr)
• PSA: 0.00000
• Density: 1.933±0.06 g/cm3(Predicted)
• LogP: 3.99740
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 283.84260
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-1-(bromomethyl)-4-chlorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)Br)CBr

Technology Process of 2-Bromo-1-(bromomethyl)-4-chlorobenzene

There total 10 articles about 2-Bromo-1-(bromomethyl)-4-chlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-bromo-4-chloro-1-methyl-benzene (27139-97-5) → 2-bromo-4-chlorobenzyl bromide (33924-45-7)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; for 24h; Inert atmosphere; Reflux;

Reference yield: 75.0%

4-Chloro-2-nitrobenzaldehyde (5551-11-1) → 2-bromo-4-chlorobenzyl bromide (33924-45-7)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; at 90 ℃; for 24h;

Reference yield: 57.0%

→ diethyl (2-bromo-4-chlorobenzyl)methyl-malonate (66192-10-7) + 2-bromo-4-chlorobenzyl bromide (33924-45-7)

Guidance literature:

upstream raw materials:

2-bromo-4-chloro-1-methyl-benzene

para-chlorotoluene

(2-bromo-4-chloro-phenyl)methanol

2-bromo-4-chlorobenzaldehyde

Downstream raw materials:

2-(2-Bromo-4-chloro-benzyl)-malonic acid diethyl ester

diethyl <(2-bromo-4-chlorophenyl)methyl>phosphonate

1-(2-bromo-4-chlorobenzyl)-2-acetylpyrrole

3-<2-(4'-chlorophenyl)ethyl>-5-methyl-2-thiophenecarboxylic acid