27139-97-5

Basic information

• Product Name: 2-Bromo-4-chlorotoluene
• Synonyms: 2-BROMO-4-CHLOROTOLUENE;2-Benzyloxyphenylacetonitrile;2-Bromo-4-chloro-1-methylbenzene;2-Bromo-4-chlorotoluene ,98%;Benzene, 2-bromo-4-chloro-1-methyl-
• CAS NO: 27139-97-5
• Molecular Formula: C₇H₆BrCl
• Molecular Weight: 205.48
• Product Categories: Aromatic Halides (substituted);Halogen toluene;Bromine Compounds;Chlorine Compounds
• Mol File: 27139-97-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 75-77°C
• Boiling Point: 112°C 20mm
• Flash Point: 100.4 °C
• Appearance: /
• Density: 1,54 g/cm3
• Vapor Pressure: 0.173mmHg at 25°C
• Refractive Index: 1.5720-1.5760
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-Bromo-4-chlorotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-chlorotoluene(27139-97-5)
• EPA Substance Registry System: 2-Bromo-4-chlorotoluene(27139-97-5)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 36/37/38-51/53-22-36/38
• Safety Statements: 26-36/37/39-61-37
• HazardClass: IRRITANT
• Hazardous Substances Data: 27139-97-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to pale yellow liquid

InChI:InChI=1/C7H6BrCl/c1-5-2-3-6(9)4-7(5)8/h2-4H,1H3

Upstream product

• 106-43-4 para-chlorotoluene 
• 95-46-5 2-methylphenyl bromide 
• 119-32-4 4-Methyl-3-nitroanilin 
• 106-38-7 para-bromotoluene 
• 99-99-0 1-methyl-4-nitrobenzene 
• 95-79-4 5-chloro-2-methyl-benzenamine 
• 7745-93-9 2-bromo-4-nitrotoluene 
• 7745-91-7 3-bromo-4-methylaniline 
• 7745-87-1 3-bromo-4-methyl-aniline; hydrochloride 

Downstream Products

• 5306-98-9 5-chloro-2-methyl-phenol 
• 936-08-3 2-bromo-4-chlorobenzoic acid 
• 148839-44-5 2-(5-Chloro-2-methyl-phenyl)-thiophene-3-carboxylic acid diethylamide 
• 63121-56-2 3-(5-Chloro-2-methyl-phenyl)-2,2,4,4-tetramethyl-pentan-3-ol 
• 116779-74-9 2-bromo-4-chlorobenzoyl chloride 
• 58966-34-0 5-chloro-2-methylbenzaldehyde 
• 1093868-70-2 tert-butyl 3-(5-chloro-2-methylphenyl)-3-oxopropyl(methyl)carbamate 
• 1241898-40-7 tert-butyl 4-(5-chloro-2-methylbenzoyl)piperidine-1-carboxylate 
• 942143-07-9 (R)-tert-butyl 3-(5-chloro-2-methylbenzoyl)piperidine-1-carboxylate 
• 33924-45-7 2-bromo-4-chlorobenzyl bromide 

Relevant articles and documents

Preparation method of 2 -bromo -4-chlorobenzaldehyde

The invention relates to a preparation method of 2 -bromo -4-chlorobenzaldehyde and belongs to the field of medicinal chemistry. The preparation method can obtain 2 -bromo -4-chlorobenzaldehyde by taking nitrotoluene as a starting material through substitution, reduction, substitution, substitution, substitution, hydrolysis and elimination reaction. Compared with the prior art, the method shortens the reaction time, the reaction temperature is higher 120 °C or higher, the reaction conditions are mild, the yield of the obtained product is about 70% and more than 90%. The reaction temperature is reduced, high-boiling-point solvent is not needed to participate in the reaction, the post-treatment is simple, and the method is more suitable for industrial production with strict safety and environmental protection.

HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION

A metallocene compound is represented by the formula (1): wherein: M is a Group 3, 4, 5 or 6 transition metal atom, or a lanthanide metal atom, or actinide metal atom, preferably a Group 4 transition metal atom selected from titanium, zirconium or hafnium; E is a substituted or unsubstituted monocyclic or polycyclic arenyl ligand pi-bonded to M; A is a substituted or unsubstituted polycyclic arenyl ligand that is pi-bonded to M and has a different ring structure than the E ligand; at least one of the A and E ligands includes at least one halogen substituent directly bonded to an sp2 carbon at a bondable ring position; Y is a bridging group containing at least one Group 13, 14, 15, or 16 element and any single position of the ring structure of A and to any single position of the ring structure of E; and y is zero or 1, indicating the absence (y = 0) or presence (y =1) of Y; and each X is a univalent anionic ligand, or two X are joined and bound to the metal atom to form a metallocycle ring, or two X are joined to form a chelating ligand, a diene ligand, or an alkylidene ligand; provided that when E is an unsubstituted cyclopentadienyl ligand, either y is one or A is not 2-bromofluorenyl or 2,7-dibromofluorenyl.

Halogen substituted metallocene compounds for olefin polymerization

A metallocene compound is represented by the formula (1): wherein: M is a Group 3, 4, 5 or 6 transition metal atom, or a lanthanide metal atom, or actinide metal atom, preferably a Group 4 transition metal atom selected from titanium, zirconium or hafnium; E is a substituted or unsubstituted monocyclic or polycyclic arenyl ligand pi-bonded to M; A is a substituted or unsubstituted polycyclic arenyl ligand that is pi-bonded to M and has a different ring structure than the E ligand; at least one of the A and E ligands includes at least one halogen substituent directly bonded to an sp2 carbon at a bondable ring position; Y is a bridging group containing at least one Group 13, 14, 15, or 16 element and any single position of the ring structure of A and to any single position of the ring structure of E; and y is zero or 1, indicating the absence (y=0) or presence (y=1) of Y; and each X is a univalent anionic ligand, or two X are joined and bound to the metal atom to form a metallocycle ring, or two X are joined to form a chelating ligand, a diene ligand, or an alkylidene ligand; provided that when E is an unsubstituted cyclopentadienyl ligand, either y is one or A is not 2-bromofluorenyl or 2,7-dibromofluorenyl.