3-ETHOXY-4-HYDROXYBENZALDEHYDE OXIME

Base Information

• Chemical Name: 3-ETHOXY-4-HYDROXYBENZALDEHYDE OXIME
• CAS No.: 34184-93-5
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.191
• Hs Code.: 2928000090
• Mol file: 34184-93-5.mol

Synonyms:3-ethoxy-4-hydroxybenzaldoxime;3-Aethoxy-4-hydroxy-benzaldehyd-oxim;Benzaldehyde,3-ethoxy-4-hydroxy-,oxime;2-ethoxy-4-[(hydroxyimino)methyl]phenol;3-ethoxy-4-hydroxy-benzaldehyde-oxime;2-ethoxy-4-[(1E)-(hydroxyimino)methyl]phenol;

Chemical Property of 3-ETHOXY-4-HYDROXYBENZALDEHYDE OXIME

Chemical Property:

• PSA: 62.05000
• LogP: 1.59900

Purity/Quality:

97% ^*data from raw suppliers

2-ethoxy-4-[(hydroxyimino)methyl]phenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ETHOXY-4-HYDROXYBENZALDEHYDE OXIME

There total 4 articles about 3-ETHOXY-4-HYDROXYBENZALDEHYDE OXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

4-hydroxy-3-ethoxybenzaldehyde (121-32-4) → 3-ethoxy-4-hydroxybenzaldoxime (34184-93-5)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In water; at 80 ℃; for 2h;

DOI:10.1016/S0968-0896(01)00084-0

Reference yield:

2-ethoxymethoxy-5-trans-propenyl-phenol → 3-ethoxy-4-hydroxybenzaldoxime (34184-93-5)

Guidance literature:

Multi-step reaction with 4 steps

1: aqueous KOH

2: aq.-ethanolic H₂SO₄

3: ozone; chloroform

With potassium hydroxide; chloroform; sulfuric acid; ozone;

Reference yield:

2-ethoxy-1-ethoxymethoxy-4-trans-propenyl-benzene → 3-ethoxy-4-hydroxybenzaldoxime (34184-93-5)

Guidance literature:

Multi-step reaction with 3 steps

1: aq.-ethanolic H₂SO₄

2: ozone; chloroform

With chloroform; sulfuric acid; ozone;

upstream raw materials:

4-hydroxy-3-ethoxybenzaldehyde

2-ethoxy-4-(prop-1-en-1-yl)phenol

Downstream raw materials:

3-ethoxy-4-hydroxybenzonitrile

4-hydroxy-3-ethoxybenzylamine hydrochloride

Refernces

• 1、 Ley, Jakob P,Bertram, Heinz-Jürgen. "Hydroxy- or methoxy-substituted benzaldoximes and benzaldehyde-O-alkyloximes as tyrosinase inhibitors". . p. 1879 - 1885. Retrieved 2007/10/03.