2-(2-Acetyl-4-fluorophenoxy)acetic acid

Base Information

Chemical Name:2-(2-Acetyl-4-fluorophenoxy)acetic acid
CAS No.:34848-65-2
Molecular Formula:C10H9FO4
Molecular Weight:212.177
Hs Code.:
DSSTox Substance ID:DTXSID70470155
Wikidata:Q82298146
Mol file:34848-65-2.mol

Synonyms:2-(2-Acetyl-4-fluorophenoxy)acetic acid;34848-65-2;SCHEMBL718460;DTXSID70470155;REIYOIMWAWBCSE-UHFFFAOYSA-N;(2-acetyl-4-fluorophenoxy)acetic acid;AKOS016007040;2-(2-Acetyl-4-fluorophenoxy)aceticacid;(2-Acetyl-4-fluoro-phenoxy)-acetic acid;AC-27181

Suppliers and Price of 2-(2-Acetyl-4-fluorophenoxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(2-Acetyl-4-fluorophenoxy)aceticacid 95+%
1g
$ 668.00

American Custom Chemicals Corporation
2-(2-ACETYL-4-FLUOROPHENOXY)ACETIC ACID 95.00%
1G
$ 1379.70

American Custom Chemicals Corporation
2-(2-ACETYL-4-FLUOROPHENOXY)ACETIC ACID 95.00%
5MG
$ 495.79

Total 7 raw suppliers

Chemical Property of 2-(2-Acetyl-4-fluorophenoxy)acetic acid

Chemical Property:

PSA：63.60000
LogP:1.49170
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:212.04848693
Heavy Atom Count:15
Complexity:254

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2-Acetyl-4-fluorophenoxy)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=CC(=C1)F)OCC(=O)O

Technology Process of 2-(2-Acetyl-4-fluorophenoxy)acetic acid

There total 5 articles about 2-(2-Acetyl-4-fluorophenoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 34849-57-5
(2-acetyl-4-fluorophenoxy)acetic acid ethyl ester

: 34848-65-2
2-(2-acetyl-4-fluorophenoxy)acetic acid

Guidance literature:: With water; potassium carbonate; for 3h; Reflux;
DOI:10.1021/jm800532x

Reference yield: 57.0%

: 394-32-1
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one

: 79-11-8
chloroacetic acid

: 34848-65-2
2-(2-acetyl-4-fluorophenoxy)acetic acid

Guidance literature:: With sodium hydroxide; for 3.5h; Heating;
DOI:10.1021/jm050462t

Reference yield:

: 394-32-1
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one

: 34848-65-2
2-(2-acetyl-4-fluorophenoxy)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 90 °C

2: aq. NaOH / tetrahydrofuran

With sodium hydroxide; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm061428x