methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate

Base Information

Chemical Name:methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate
CAS No.:96086-52-1
Molecular Formula:C₁₄H₁₆N₂OS₂
Molecular Weight:292.426
Hs Code.:
Mol file:96086-52-1.mol

Synonyms:methyl (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline-2-carbodithioate;(S)-3-Hydroxymethyl-1,3,4,9-tetrahydro-β-carboline-2-carbodithioic acid methyl ester;

Suppliers and Price of methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate

Chemical Property:

Vapor Pressure:4.52E-11mmHg at 25°C
Boiling Point:506.2°Cat760mmHg
Flash Point:260°C
PSA：96.65000
Density:1.383g/cm³
LogP:2.47270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate

There total 5 articles about methyl 1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 96149-78-9
(S)-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-3-yl)methanol

: 74-88-4
methyl iodide

: 96086-52-1
methyl (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-β-carboline-2-carbodithioate

Guidance literature:: With carbon disulfide; triethylamine; In methanol; water; ethyl acetate;

Reference yield:

: 7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8
(S)-tryptophan methyl ester hydrochloride

: 96086-52-1
methyl (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-β-carboline-2-carbodithioate

Guidance literature:: Multi-step reaction with 3 steps

1: 82.9 percent / methanol / Ambient temperature

2: 76 percent / NaBH₄ / ethanol; H₂O / 1.) room temp., 2 h; 2.) reflux, 3 h

3: 1.) Et₃N / 1.) MeOH, H₂O, room temp., 30 min; 2.) room temp., 1.5 h

With sodium tetrahydroborate; triethylamine; In methanol; ethanol; water;
DOI:10.1248/cpb.35.3262

Reference yield:

: 83159-19-7
methyl (S)-(-)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole-3-carboxylate hydrochloride

: 96086-52-1
methyl (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-β-carboline-2-carbodithioate

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / NaBH₄ / ethanol; H₂O / 1.) room temp., 2 h; 2.) reflux, 3 h

2: 1.) Et₃N / 1.) MeOH, H₂O, room temp., 30 min; 2.) room temp., 1.5 h

With sodium tetrahydroborate; triethylamine; In ethanol; water;
DOI:10.1248/cpb.35.3262