tert-Butyl 4-bromo-3,5-dimethylphenylcarbamate

Base Information

Chemical Name:tert-Butyl 4-bromo-3,5-dimethylphenylcarbamate
CAS No.:361436-27-3
Molecular Formula:C13H18BrNO2
Molecular Weight:300.19200
Hs Code.:2924299090
Mol file:361436-27-3.mol

Synonyms:tert-butyl 4-bromo-3,5-dimethylphenylcarbamate;N-Boc 4-bromo-3,5-dimethylaniline;

Suppliers and Price of tert-Butyl 4-bromo-3,5-dimethylphenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Boc4-bromo-3,5-dimethylaniline
25mg
$ 55.00

TRC
N-Boc4-bromo-3,5-dimethylaniline
10mg
$ 45.00

American Custom Chemicals Corporation
TERT-BUTYL-(4-BROMO-3,5-DIMETHYLPHENYL)CARBAMATE 95.00%
5MG
$ 505.14

Alichem
tert-Butyl(4-bromo-3,5-dimethylphenyl)carbamate
1g
$ 430.92

AK Scientific
N-Boc4-bromo-3,5-dimethylaniline
250mg
$ 317.00

Activate Scientific
tert-Butyl(4-bromo-3,5-dimethylphenyl)carbamate 98%
100 mg
$ 218.00

Total 9 raw suppliers

Chemical Property of tert-Butyl 4-bromo-3,5-dimethylphenylcarbamate

Chemical Property:

Boiling Point:312.6±42.0 °C(Predicted)
PKA:12.99±0.70(Predicted)
PSA：38.33000
Density:1.321±0.06 g/cm3(Predicted)
LogP:4.48590
Storage Temp.:Room temperature.

Purity/Quality:

98% ^*data from raw suppliers

N-Boc4-bromo-3,5-dimethylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl 4-bromo-3,5-dimethylphenylcarbamate

There total 2 articles about tert-Butyl 4-bromo-3,5-dimethylphenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 7463-51-6
4-bromo-3,5-dimethylphenol

: 361436-27-3
tert-butyl (4-bromo-3,5-dimethylphenyl)carbamate

Guidance literature:: With pyridine; dmap; In dichloromethane; for 20h; Inert atmosphere; Reflux;
DOI:10.1021/acs.orglett.1c03926

Reference yield:

: di-tert-butyl pyrocarbamate

: 59557-90-3
4-bromo-3,5-dimethylaniline

: 361436-27-3
tert-butyl (4-bromo-3,5-dimethylphenyl)carbamate

Guidance literature:: In tetrahydrofuran;

Reference yield: 97.0%

: 74-88-4
methyl iodide

: 361436-27-3
tert-butyl (4-bromo-3,5-dimethylphenyl)carbamate

: tert-butyl (4-bromo-3,5-dimethylphenyl)(methyl)carbamate

Guidance literature:: tert-butyl (4-bromo-3,5-dimethylphenyl)carbamate; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.0833333h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.8b00182