3-(4-Methylphenyl)-1,2,4-oxadiazol-5-amine

Base Information

Chemical Name:3-(4-Methylphenyl)-1,2,4-oxadiazol-5-amine
CAS No.:3663-38-5
Molecular Formula:C₉H₉N₃O
Molecular Weight:175.19
Hs Code.:
DSSTox Substance ID:DTXSID701264759
Mol file:3663-38-5.mol

Synonyms:3-(4-methylphenyl)-1,2,4-oxadiazol-5-amine;3663-38-5;DTXSID701264759;AKOS011759205;EN300-128094

Suppliers and Price of 3-(4-Methylphenyl)-1,2,4-oxadiazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(4-Methylphenyl)-1,2,4-oxadiazol-5-amine

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:175.074561919
Heavy Atom Count:13
Complexity:168

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NOC(=N2)N

Technology Process of 3-(4-Methylphenyl)-1,2,4-oxadiazol-5-amine

There total 9 articles about 3-(4-Methylphenyl)-1,2,4-oxadiazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 114006-43-8
Tetrazol-1-yl-p-tolyl-methanone oxime

: 16013-06-2
3-(4-methylphenyl)-1,2,4-oxadiazole

: 3663-38-5
3-p-tolyl-[1,2,4]oxadiazol-5-ylamine

Guidance literature:: In xylene; for 0.333333h; Heating;

Reference yield:

: 36288-37-6
N-hydroxy-4-methylbenzenecarboximidoyl chloride

: 3663-38-5
3-p-tolyl-[1,2,4]oxadiazol-5-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / triethylamine / dioxane / 48 h / Ambient temperature

2: 10 percent / xylene / 0.33 h / Heating

With triethylamine; In 1,4-dioxane; xylene;

Reference yield:

: 19227-13-5
p-toluamidoxime

: 3663-38-5
3-p-tolyl-[1,2,4]oxadiazol-5-ylamine

Guidance literature:: Multi-step reaction with 5 steps

1: Py / CHCl₃ / 80 °C

2: N₂H₄*H₂O / methanol / 0 °C

3: NaNO₂, aq. HCl / acetic acid / 5 °C

4: (i) toluene, (heating), (ii) /BRN= 1718733/, (heating)

5: H₂O / Heating

With pyridine; hydrogenchloride; water; hydrazine hydrate; sodium nitrite; In methanol; chloroform; acetic acid;