N-(2-aminophenyl)-2-hydroxybenzamide

Base Information

Chemical Name:N-(2-aminophenyl)-2-hydroxybenzamide
CAS No.:3679-66-1
Molecular Formula:C13H12N2O2
Molecular Weight:228.25
Hs Code.:
DSSTox Substance ID:DTXSID20383988
Mol file:3679-66-1.mol

Synonyms:N-(2-aminophenyl)-2-hydroxybenzamide;3679-66-1;2'-aminosalicylanilide;benzamide,n-(2-aminophenyl)-2-hydroxy-;Oprea1_094599;CBDivE_012178;DTXSID20383988;STK134417;AKOS000104414;CCG-233876

Suppliers and Price of N-(2-aminophenyl)-2-hydroxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(2-aminophenyl)-2-hydroxybenzamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:228.089877630
Heavy Atom Count:17
Complexity:270

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2N)O

Technology Process of N-(2-aminophenyl)-2-hydroxybenzamide

There total 4 articles about N-(2-aminophenyl)-2-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 37183-26-9
salicylic acid-(2-nitro-anilide)

: 3679-66-1
N-(2-aminophenyl)salicylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; at 20 ℃;
DOI:10.1016/S0014-827X(01)01146-6

Reference yield:

: 493-53-8
sodium O-acetylsalicylate

: 3679-66-1
N-(2-aminophenyl)salicylamide

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / 2.33 h / 0 - 20 °C

2: 84 percent / benzene / 16 h / Heating

3: 89 percent / H₂ / Pd/C / acetic acid / 20 °C

With thionyl chloride; hydrogen; palladium on activated charcoal; In acetic acid; benzene;
DOI:10.1016/S0014-827X(01)01146-6

Reference yield:

: 5538-51-2
O-acetylsalicyloyl chloride

: 3679-66-1
N-(2-aminophenyl)salicylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / benzene / 16 h / Heating

2: 89 percent / H₂ / Pd/C / acetic acid / 20 °C

With hydrogen; palladium on activated charcoal; In acetic acid; benzene;
DOI:10.1016/S0014-827X(01)01146-6