Boronic acid, [4-[(1,1-dimethylethyl)[[(1,1-dimethylethyl)dimethylsilyl]oxy]amino]phenyl] -

Base Information

Chemical Name:Boronic acid, [4-[(1,1-dimethylethyl)[[(1,1-dimethylethyl)dimethylsilyl]oxy]amino]phenyl] -
CAS No.:371248-60-1
Molecular Formula:C16H30BNO3Si
Molecular Weight:323.316
Hs Code.:
Mol file:371248-60-1.mol

Synonyms:PNN-Si;tris[4-(N-tert-butyl-N-[tert-butyldimethylsiloxyl]amino)phenyl]boroxin;t-BuNO-BA;4-(N-tert-butyl-N-[tert-butyldimethylsiloxyl]amino)phenylboronic acid;4-(tert-butyl(tertbutyldimethylsilyloxy)amino)phenylboronic acid;

Suppliers and Price of Boronic acid, [4-[(1,1-dimethylethyl)[[(1,1-dimethylethyl)dimethylsilyl]oxy]amino]phenyl] -

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Boronic acid, [4-[(1,1-dimethylethyl)[[(1,1-dimethylethyl)dimethylsilyl]oxy]amino]phenyl] -

Chemical Property:

PSA：52.93000
LogP:2.90810

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Boronic acid, [4-[(1,1-dimethylethyl)[[(1,1-dimethylethyl)dimethylsilyl]oxy]amino]phenyl] -

There total 3 articles about Boronic acid, [4-[(1,1-dimethylethyl)[[(1,1-dimethylethyl)dimethylsilyl]oxy]amino]phenyl] - which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 168848-31-5
1-[N-tert-butyl-N-(tert-butyldimethylsilyloxy)amino]-4-bromobenzene

: 371248-60-1
tris[4-(N-tert-butyl-N-[tert-butyldimethylsiloxyl]amino)phenyl]boroxin

: 4-(N-tert-butyl-N-[tert-butyldimethylsiloxyl]amino)phenylboronic acid boroxin cyclic trimer

Guidance literature:: 1-[N-tert-butyl-N-(tert-butyldimethylsilyloxy)amino]-4-bromobenzene; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 1h;

With Triisopropyl borate; In tetrahydrofuran; pentane; at -78 - 20 ℃;

With ammonium chloride; In tetrahydrofuran; pentane; at 20 ℃; for 1h; Title compound not separated from byproducts;
DOI:10.1021/ja0343813

Reference yield:

: 106-37-6
1.4-dibromobenzene

: 371248-60-1
tris[4-(N-tert-butyl-N-[tert-butyldimethylsiloxyl]amino)phenyl]boroxin

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / diethyl ether; hexane / 1 h / -78 °C

1.2: diethyl ether; hexane / -78 - 20 °C

2.1: 4.5 g / imidazole / dimethylformamide / 24 h / 50 °C

3.1: tert-butyllithium / tetrahydrofuran; pentane / 1 h / -78 °C

3.2: triisopropyl borate / tetrahydrofuran; pentane / -78 - 20 °C

3.3: aq. NH₄Cl / tetrahydrofuran; pentane / 1 h / 20 °C

With 1H-imidazole; n-butyllithium; tert.-butyl lithium; In tetrahydrofuran; diethyl ether; hexane; N,N-dimethyl-formamide; pentane;
DOI:10.1021/ja0343813

Reference yield:

: 40686-35-9
1-[N-tert-butyl-N-(hydroxylamino)]-4-bromobenzene

: 371248-60-1
tris[4-(N-tert-butyl-N-[tert-butyldimethylsiloxyl]amino)phenyl]boroxin

Guidance literature:: Multi-step reaction with 2 steps

1.1: 4.5 g / imidazole / dimethylformamide / 24 h / 50 °C

2.1: tert-butyllithium / tetrahydrofuran; pentane / 1 h / -78 °C

2.2: triisopropyl borate / tetrahydrofuran; pentane / -78 - 20 °C

2.3: aq. NH₄Cl / tetrahydrofuran; pentane / 1 h / 20 °C

With 1H-imidazole; tert.-butyl lithium; In tetrahydrofuran; N,N-dimethyl-formamide; pentane;
DOI:10.1021/ja0343813