Acetamide, N-(4-fluorophenyl)-2,2-dichloro-

Base Information

Chemical Name:Acetamide, N-(4-fluorophenyl)-2,2-dichloro-
CAS No.:37540-41-3
Molecular Formula:C8H6Cl2FNO
Molecular Weight:222.046
Hs Code.:
DSSTox Substance ID:DTXSID201274517
Nikkaji Number:J2.235.433G
ChEMBL ID:CHEMBL1240997

Synonyms:2,2-dichloro-N-(4-fluorophenyl)acetamide;Acetamide, N-(4-fluorophenyl)-2,2-dichloro-;N-(4-fluorophenyl)-2,2-dichloroacetamide;37540-41-3;CHEMBL1240997;DTXSID201274517;STL261062;AKOS003267596

Suppliers and Price of Acetamide, N-(4-fluorophenyl)-2,2-dichloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetamide, N-(4-fluorophenyl)-2,2-dichloro-

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:220.9810474
Heavy Atom Count:13
Complexity:181

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)C(Cl)Cl)F

Technology Process of Acetamide, N-(4-fluorophenyl)-2,2-dichloro-

There total 5 articles about Acetamide, N-(4-fluorophenyl)-2,2-dichloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 5,5-dichloro-meldrum’s acid

: 371-40-4
4-fluoroaniline

: 37540-41-3
N-(4-fluorophenyl)-2,2-dichloroacetamide

Guidance literature:: In ethyl acetate; at 20 ℃; for 16h; Solvent; Sealed tube;
DOI:10.1021/acs.orglett.1c00850

Reference yield: 85.0%

: 79-36-7
dichloroacethyl chloride

: 371-40-4
4-fluoroaniline

: 37540-41-3
N-(4-fluorophenyl)-2,2-dichloroacetamide

Guidance literature:: With pyridine; In toluene; at 5 ℃;
DOI:10.1021/jf051458t

Reference yield: 81.0%

: 2713-85-1
N-(4-fluorophenyl)-3-oxobutanamide

: 37540-41-3
N-(4-fluorophenyl)-2,2-dichloroacetamide

Guidance literature:: With N-chloro-succinimide; C₂₀H₂₇N₃O₂S; In methanol; at 25 ℃; for 2h; Darkness; Inert atmosphere;
DOI:10.1021/acs.orglett.0c02701