3-(Pyrrolidin-3-yl)-1H-indole

Base Information

Chemical Name:3-(Pyrrolidin-3-yl)-1H-indole
CAS No.:3766-02-7
Molecular Formula:C12H14N2
Molecular Weight:186.257
Hs Code.:2933990090
European Community (EC) Number:899-471-0
DSSTox Substance ID:DTXSID70593499
Nikkaji Number:J1.480.668G
Mol file:3766-02-7.mol

Synonyms:3-(Pyrrolidin-3-yl)-1H-indole;3766-02-7;3-pyrrolidin-3-yl-1H-indole;3-(indol-3-yl)pyrrolidine;3-pyrrolidine-3-yl-1H-indole;SCHEMBL1445576;DTXSID70593499;QEHMBCDTVQBATA-UHFFFAOYSA-N;AKOS005362599;EN300-318385;F2147-1322

Suppliers and Price of 3-(Pyrrolidin-3-yl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(Pyrrolidin-3-yl)-1H-indole 97%
5g
$ 1404.00

Crysdot
3-(Pyrrolidin-3-yl)-1H-indole 97%
1g
$ 599.00

Crysdot
3-(Pyrrolidin-3-yl)-1H-indole 97%
10g
$ 1925.00

Chemenu
3-(Pyrrolidin-3-yl)-1H-indole 95%+
10g
$ 1814.00

Chemenu
3-(Pyrrolidin-3-yl)-1H-indole 95%+
1g
$ 566.00

Chemenu
3-(Pyrrolidin-3-yl)-1H-indole 95%+
5g
$ 1323.00

Alichem
3-(Pyrrolidin-3-yl)-1h-indole
1g
$ 688.00

Alichem
3-(Pyrrolidin-3-yl)-1h-indole
250mg
$ 272.25

Total 4 raw suppliers

Chemical Property of 3-(Pyrrolidin-3-yl)-1H-indole

Chemical Property:

PSA：27.82000
LogP:2.57360
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:186.115698455
Heavy Atom Count:14
Complexity:205

Purity/Quality:

95% ^*data from raw suppliers

3-(Pyrrolidin-3-yl)-1H-indole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC1C2=CNC3=CC=CC=C32

Technology Process of 3-(Pyrrolidin-3-yl)-1H-indole

There total 6 articles about 3-(Pyrrolidin-3-yl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 10185-29-2
3-(1H-indole-3-yl)pyrrolidine-2,5-dione

: 3766-02-7
3-(pyrrolidin-3-yl)-1H-indole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 65 ℃; for 16h;

Reference yield:

: 120-72-9
indole

: 3766-02-7
3-(pyrrolidin-3-yl)-1H-indole

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / 2.5 h / Reflux

2.1: piperidine / ethanol / 5 h / 0 - 20 °C

3.1: ethanol / 2.5 h / 80 °C

4.1: acetic acid; sulfuric acid / 1.5 h / 120 °C

4.2: 18 h / 0 - 70 °C

With piperidine; sulfuric acid; acetic acid; In ethanol;
DOI:10.1016/j.bmcl.2012.07.070

Reference yield:

: 10184-93-7
(3-Indolyl)bernsteinsaeuredinitril

: 3766-02-7
3-(pyrrolidin-3-yl)-1H-indole

Guidance literature:: (3-Indolyl)bernsteinsaeuredinitril; With sulfuric acid; acetic acid; at 120 ℃; for 1.5h;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 70 ℃; for 18h;
DOI:10.1016/j.bmcl.2012.07.070