4-Tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde

Base Information

Chemical Name:4-Tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde
CAS No.:378749-92-9
Molecular Formula:C24H25ClO3Si
Molecular Weight:424.999
Hs Code.:
DSSTox Substance ID:DTXSID401134741

Synonyms:VNXFLNZDSPGBFQ-UHFFFAOYSA-N;DTXSID401134741;4-tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde;378749-92-9;2-(Chloromethyl)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-6-hydroxybenzaldehyde

Suppliers and Price of 4-Tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:424.1261489
Heavy Atom Count:29
Complexity:505

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OC3=CC(=C(C(=C3)O)C=O)CCl

Technology Process of 4-Tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde

There total 2 articles about 4-Tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxy benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 705-76-0
3,5-dimethoxybenzyl alcohol

: 378749-92-9
4-tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: POCl₃ / 0.33 h / 25 °C

1.2: 93 percent / 2 h / 25 - 75 °C

2.1: 96 percent / BBr₃ / CH₂Cl₂ / 20 h / 25 °C

3.1: 97 percent / imidazole / CH₂Cl₂; tetrahydrofuran / 12 h / 25 °C

With 1H-imidazole; boron tribromide; trichlorophosphate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja011364+

Reference yield:

: 166322-67-4
2-(chloromethyl)-4,6-dimethoxy-benzaldehyde

: 378749-92-9
4-tert-butyldiphenylsiloxy-2-chloromethyl-6-hydroxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / BBr₃ / CH₂Cl₂ / 20 h / 25 °C

2: 97 percent / imidazole / CH₂Cl₂; tetrahydrofuran / 12 h / 25 °C

With 1H-imidazole; boron tribromide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja011364+