5-Hydroxy-1,8-naphthyridin-2(1H)-one

Base Information

Chemical Name:5-Hydroxy-1,8-naphthyridin-2(1H)-one
CAS No.:37905-96-7
Molecular Formula:C8H6N2O2
Molecular Weight:162.14500
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40493614
Wikidata:Q82340402
Mol file:37905-96-7.mol

Synonyms:5-Hydroxy-1,8-naphthyridin-2(1H)-one;37905-96-7;1,8-Naphthyridine-2,5(1H,8H)-dione;1,8-dihydro-1,8-naphthyridine-2,5-dione;57773-13-4;5-hydroxy-1,2-dihydro-1,8-naphthyridin-2-one;[1,8]Naphthyridine-2,5-diol;SCHEMBL2026652;DTXSID40493614;2,5-dihydroxy-1,8-naphthyridine;MFCD13181697;AKOS006288568;AKOS027252901;AS-37489;FT-0742377

Suppliers and Price of 5-Hydroxy-1,8-naphthyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Hydroxy-1,8-naphthyridin-2(1H)-one
50mg
$ 130.00

Crysdot
5-Hydroxy-1,8-naphthyridin-2(1H)-one 95+%
1g
$ 395.00

Crysdot
5-Hydroxy-1,8-naphthyridin-2(1H)-one 95+%
5g
$ 1385.00

Alichem
5-Hydroxy-1,8-naphthyridin-2(1H)-one
1g
$ 410.97

Alichem
5-Hydroxy-1,8-naphthyridin-2(1H)-one
250mg
$ 168.54

Alichem
5-Hydroxy-1,8-naphthyridin-2(1H)-one
5g
$ 1396.00

AccelPharmtech
5-hydroxy-1,8-Naphthyridin-2(1H)-one 97.00%
25G
$ 6000.00

Total 10 raw suppliers

Chemical Property of 5-Hydroxy-1,8-naphthyridin-2(1H)-one

Chemical Property:

Boiling Point:624.0±55.0 °C(Predicted)
PKA:11.45±0.20(Predicted)
PSA：65.98000
Density:1.425±0.06 g/cm3(Predicted)
LogP:0.62870
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:162.042927438
Heavy Atom Count:12
Complexity:350

Purity/Quality:

97% ^*data from raw suppliers

5-Hydroxy-1,8-naphthyridin-2(1H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)NC2=C1C(=O)C=CN2

Technology Process of 5-Hydroxy-1,8-naphthyridin-2(1H)-one

There total 4 articles about 5-Hydroxy-1,8-naphthyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 37905-96-7
1,8-naphthyridine-2,5-diol

Guidance literature:

Reference yield:

: 5154-00-7,59315-47-8
6-amino-pyridin-2-ol

: 37905-96-7
1,8-naphthyridine-2,5-diol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.5 h / 110 °C

2: NaOH / H₂O / 1.75 h / 100 °C

3: 2.5 g / diphenyl ether / 9 h / Heating

With sodium hydroxide; In diphenylether; water;

Reference yield:

: 91045-50-0
diethyl (6'-methylpyridin-2'-yl)aminomethylenemalonate

: 37905-96-7
1,8-naphthyridine-2,5-diol

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / H₂O / 1.75 h / 100 °C

2: 2.5 g / diphenyl ether / 9 h / Heating

With sodium hydroxide; In diphenylether; water;