alpha,epsilon-Dibenzoyl-DL-lysine

Base Information

• Chemical Name: alpha,epsilon-Dibenzoyl-DL-lysine
• CAS No.: 1946-96-9
• Molecular Formula: C₂₀H₂₂N₂O₄
• Molecular Weight: 354.406
• NSC Number: 46040
• DSSTox Substance ID: DTXSID20286480
• ChEMBL ID: CHEMBL1205679
• Mol file: 1946-96-9.mol

Synonyms:alpha,epsilon-Dibenzoyl-DL-lysine;32513-92-1;1946-96-9;n2,n6-dibenzoyllysine;Dibenzoyl-dl-lysine;NSC46040;CHEMBL1205679;SCHEMBL10801036;2,6-bis(benzamido)hexanoic acid;DTXSID20286480;WZWYZPFOTAVDKN-UHFFFAOYSA-N;MFCD00059684;NSC-46040;HY-W141976;B0208;CS-0201766;T70776

Chemical Property of alpha,epsilon-Dibenzoyl-DL-lysine

Chemical Property:

• Boiling Point: 700.5°Cat760mmHg
• Flash Point: 377.5°C
• Density: 1.213g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 354.15795719
• Heavy Atom Count: 26
• Complexity: 468

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NCCCCC(C(=O)O)NC(=O)C2=CC=CC=C2

Technology Process of alpha,epsilon-Dibenzoyl-DL-lysine

There total 2 articles about alpha,epsilon-Dibenzoyl-DL-lysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-lysine (56-87-1,3506-25-0) + benzoyl chloride (98-88-4) → N,N'-di(benzoyl)lysine (1946-96-9)

Guidance literature:

With sodium hydroxide; for 2h; Ambient temperature; pH=10;

DOI:10.1021/jm00021a014

Reference yield:

→ N,N'-di(benzoyl)lysine (1946-96-9)

Guidance literature:

With hydrogenchloride; 2-methoxy-ethanol;

Reference yield:

N,N'-di(benzoyl)lysine (1946-96-9) → C20H24N2O3 (70548-38-8)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄

2: LiBH₄

With lithium borohydride; sulfuric acid;

DOI:10.1021/jm00192a006

upstream raw materials:

L-lysine

benzoyl chloride

Downstream raw materials:

(S)-2,6-Bis-benzoylamino-hexanoic acid methyl ester

(S)-2,6-Bis-(2,6-bis-benzoylamino-hexanoylamino)-hexanoic acid methyl ester

C₂₀H₂₄N₂O₃