N-Ethoxycarbonyl-3-nitro-o-toluidine

Base Information

Chemical Name:N-Ethoxycarbonyl-3-nitro-o-toluidine
CAS No.:381670-28-6
Molecular Formula:C10H12N2O4
Molecular Weight:224.21300
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60426863
Nikkaji Number:J31.228B
Mol file:381670-28-6.mol

Synonyms:N-Ethoxycarbonyl-3-nitro-o-toluidine;381670-28-6;Ethyl (2-methyl-3-nitrophenyl)carbamate;ethyl N-(2-methyl-3-nitrophenyl)carbamate;N-(3-Nitro-2-methylphenyl)urethan;Ethyl 2-Methyl-3-nitrophenylcarbamate;DTXSID60426863;N-Carbethoxy-3-nitro-o-toluidine;MFCD00059819;AKOS008934472;CS-0451961;E0356;FT-0726670;D90494;N-Ethoxycarbonyl-3-nitro-o-toluidine (NH2=1)

Suppliers and Price of N-Ethoxycarbonyl-3-nitro-o-toluidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
N-Ethoxycarbonyl-3-nitro-o-toluidine
25g
$ 178.00

Crysdot
Ethyl(2-methyl-3-nitrophenyl)carbamate 95+%
100g
$ 411.00

American Custom Chemicals Corporation
N-ETHOXYCARBONYL-3-NITRO-ORTHO-TOLUIDINE 98.00%
50ML
$ 3300.00

American Custom Chemicals Corporation
N-ETHOXYCARBONYL-3-NITRO-ORTHO-TOLUIDINE 98.00%
100G
$ 3210.90

Alichem
Ethyl(2-methyl-3-nitrophenyl)carbamate
100g
$ 415.00

AK Scientific
N-Ethoxycarbonyl-3-nitro-O-toluidine
25g
$ 361.00

Total 9 raw suppliers

Chemical Property of N-Ethoxycarbonyl-3-nitro-o-toluidine

Chemical Property:

Vapor Pressure:0.00341mmHg at 25°C
Melting Point:114oC
Boiling Point:282.2oC at 760 mmHg
Flash Point:124.5oC
PSA：84.15000
Density:1.292g/cm3
LogP:3.06780
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:224.07970687
Heavy Atom Count:16
Complexity:264

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Ethoxycarbonyl-3-nitro-o-toluidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=C(C(=CC=C1)[N+](=O)[O-])C

Technology Process of N-Ethoxycarbonyl-3-nitro-o-toluidine

There total 1 articles about N-Ethoxycarbonyl-3-nitro-o-toluidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 541-41-3
chloroformic acid ethyl ester

: 603-83-8
3-nitro-o-tolylamine

: 381670-28-6
(2-methyl-3-nitro-phenyl)-carbamic acid ethyl ester

Guidance literature:: In 1,4-dioxane; at 65 ℃; for 24h;
DOI:10.1021/jm031044w

Reference yield:

: 381670-28-6
(2-methyl-3-nitro-phenyl)-carbamic acid ethyl ester

: 675575-44-7
2-ethoxycarbonylamino-6-nitro-benzoic acid

Guidance literature:: With pyridine; potassium permanganate; at 80 - 95 ℃; for 1h;
DOI:10.1021/jm031044w

Reference yield:

: 381670-28-6
(2-methyl-3-nitro-phenyl)-carbamic acid ethyl ester

: 4-hydroxy-1-methyl-5-nitro-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid methyl-phenyl-amide

Guidance literature:: Multi-step reaction with 6 steps

1: 10.0 g / aq. KMnO₄; pyridine / 1 h / 80 - 95 °C

2: 6.4 g / SOCl₂ / dioxane / 40 °C

3: NaH / dimethylformamide / 5 h / 20 °C

4: NaH / dimethylformamide / 5 h / 85 °C

5: HCl / acetic acid / 6 h / 60 °C

6: SOCl₂; Et₃N / CH₂Cl₂ / 4.5 h / 0 - 20 °C

With pyridine; hydrogenchloride; potassium permanganate; thionyl chloride; sodium hydride; triethylamine; In 1,4-dioxane; dichloromethane; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm031044w