Cyclohexanemethanol, a-methyl-, 4-methylbenzenesulfonate

Base Information

• Chemical Name: Cyclohexanemethanol, a-methyl-, 4-methylbenzenesulfonate
• CAS No.: 38293-92-4
• Molecular Formula: C15H22O3S
• Molecular Weight: 282.404
• Mol file: 38293-92-4.mol

Synonyms:

Chemical Property of Cyclohexanemethanol, a-methyl-, 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Cyclohexanemethanol, a-methyl-, 4-methylbenzenesulfonate

There total 2 articles about Cyclohexanemethanol, a-methyl-, 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

rac-1-cyclohexylethanol (1193-81-3) + p-toluenesulfonyl chloride (98-59-9) → 1-cyclohexylethyl 4-methylbenzenesulfonate (38293-92-4)

Guidance literature:

With trimethylamine hydrochloride; triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.7b02117

Reference yield:

→ 1-cyclohexylethyl 4-methylbenzenesulfonate (38293-92-4)

Guidance literature:

1-Cyclohexylethanol, p-Toluolsulfochlorid;

Reference yield: 55.0%

1-cyclohexylethyl 4-methylbenzenesulfonate (38293-92-4) + bis(pinacol)diborane (73183-34-3) → 2-(1-cyclohexylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:

With silver(I) pentafluoropropionate; lithium tert-butoxide; In 1,4-dioxane; at 60 ℃; for 24h; chemoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/cjoc.201800500

upstream raw materials:

rac-1-cyclohexylethanol

p-toluenesulfonyl chloride