2-Amino-3-phenyl-5,7-di-tert-butyl-benzofurane

Base Information

Chemical Name:2-Amino-3-phenyl-5,7-di-tert-butyl-benzofurane
CAS No.:387365-63-1
Molecular Formula:C22H27NO
Molecular Weight:321.462
Hs Code.:
DSSTox Substance ID:DTXSID70464554
Nikkaji Number:J2.003.886A
Wikidata:Q82289922
Mol file:387365-63-1.mol

Synonyms:2-amino-3-phenyl-5,7-di-tert-butyl-benzofurane;387365-63-1;SCHEMBL6175096;DTXSID70464554;FXACNRGIHVMMQE-UHFFFAOYSA-N

Suppliers and Price of 2-Amino-3-phenyl-5,7-di-tert-butyl-benzofurane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Amino-3-phenyl-5,7-di-tert-butyl-benzofurane

Chemical Property:

Boiling Point:429.6±33.0 °C(Predicted)
PSA：39.16000
Density:1.046±0.06 g/cm3(Predicted)
LogP:6.85820
XLogP3:6.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:321.209264485
Heavy Atom Count:24
Complexity:426

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC2=C(C(=C1)C(C)(C)C)OC(=C2C3=CC=CC=C3)N

Technology Process of 2-Amino-3-phenyl-5,7-di-tert-butyl-benzofurane

There total 3 articles about 2-Amino-3-phenyl-5,7-di-tert-butyl-benzofurane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 252961-11-8
2,4-di-tert-butyl-6-(dimethylamino-phenyl-methyl)-phenol

: 387365-63-1
2-amino-3-phenyl-5,7-di-tert-butylbenzofuran

Guidance literature:: With sodium cyanide; In sulfolane; water; at 120 ℃; for 1h;

Reference yield:

: 96-76-4
2,4-di-tert-Butylphenol

: 387365-63-1
2-amino-3-phenyl-5,7-di-tert-butylbenzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / H₂O / 10 h / 140 °C

2: 87 percent / tetrahydrothiophene 1,1-dioxide; H₂O / 1 h / 120 °C

In sulfolane; water; 1: Mannich reaction;
DOI:10.1055/s-2003-44389

Reference yield:

: 100-52-7
benzaldehyde

: 387365-63-1
2-amino-3-phenyl-5,7-di-tert-butylbenzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / H₂O / 10 h / 140 °C

2: 87 percent / tetrahydrothiophene 1,1-dioxide; H₂O / 1 h / 120 °C

In sulfolane; water; 1: Mannich reaction;
DOI:10.1055/s-2003-44389