1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid

Base Information

Chemical Name:1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid
CAS No.:38853-85-9
Molecular Formula:C8H12O4
Molecular Weight:172.17800
Hs Code.:
European Community (EC) Number:837-980-1
DSSTox Substance ID:DTXSID90539172
Mol file:38853-85-9.mol

Synonyms:1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid;38853-85-9;1,4-dioxaspiro[4.4]nonane-9-carboxylic acid;1,4-Dioxaspiro[4.4]nonane-6-carboxylicacid;SCHEMBL4978998;DTXSID90539172;AKOS023558228;EN300-190630;F84687;Z1262515761

Suppliers and Price of 1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,4-dioxaspiro[4.4]nonane-6-carboxylicacid
100mg
$ 220.00

TRC
1,4-dioxaspiro[4.4]nonane-6-carboxylicacid
50mg
$ 155.00

TRC
1,4-dioxaspiro[4.4]nonane-6-carboxylicacid
10mg
$ 45.00

AK Scientific
1,4-Dioxaspiro[4.4]nonane-6-carboxylicacid
500mg
$ 692.00

AK Scientific
1,4-Dioxaspiro[4.4]nonane-6-carboxylicacid
250mg
$ 432.00

Total 5 raw suppliers

Chemical Property of 1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid

Chemical Property:

Boiling Point:329.9±37.0 °C(Predicted)
PSA：55.76000
Density:1.30±0.1 g/cm3(Predicted)
LogP:0.61420
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:172.07355886
Heavy Atom Count:12
Complexity:195

Purity/Quality:

98%+ ^*data from raw suppliers

1,4-dioxaspiro[4.4]nonane-6-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C2(C1)OCCO2)C(=O)O

Technology Process of 1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid

There total 5 articles about 1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 110295-58-4
1,4-dioxa-spiro[4.4]nonane-6-carboxylic acid methyl ester

: 38853-85-9
1,4-dioxaspiro[4.4]nonane-6-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In water; at 80 ℃; for 2h;

Reference yield:

: 23153-73-3
ethyl 1,4-dioxaspiro[4,4]nonane-6-carboxylate

: 38853-85-9
1,4-dioxaspiro[4.4]nonane-6-carboxylic acid

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; at 35 ℃; for 12h;
DOI:10.1016/j.bmcl.2005.03.054

Reference yield:

: 611-10-9
2-ethoxycarbonyl-1-cyclopentanone

: 38853-85-9
1,4-dioxaspiro[4.4]nonane-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: TsOH*H₂O / toluene / Heating

2: aq. KOH / dioxane / 12 h / 35 °C

With potassium hydroxide; toluene-4-sulfonic acid; In 1,4-dioxane; toluene;
DOI:10.1016/j.bmcl.2005.03.054