Ethanimidamide, 2,2,2-trifluoro-, monohydrochloride

Base Information

• Chemical Name: Ethanimidamide, 2,2,2-trifluoro-, monohydrochloride
• CAS No.: 39560-95-7
• Molecular Formula: C2H3F3N2.ClH
• Molecular Weight: 148.515
• Hs Code.: 2925290090
• Mol file: 39560-95-7.mol

Synonyms:trifluoroacetaldehyde methyl hemiacetal;2,2,2-trifluoro-1,1-dimethoxyethane;trifluoroacetamidine hydrochloride;trifluoroacetaldehyde methyl acetal;2,2,2-trifluoroacetimidamide hydrochloride;1,1,1-Trifluor-2,2,-dimethyoxyethan;Trifluoroacetaldehyde dimethyl acetal;Trifluoracetaldehyd-dimethylacetal;

Chemical Property of Ethanimidamide, 2,2,2-trifluoro-, monohydrochloride

Chemical Property:

• PSA: 49.87000
• LogP: 2.08670

Purity/Quality:

97% ^*data from raw suppliers

2,2,2-Trifluoroacetimidamidehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanimidamide, 2,2,2-trifluoro-, monohydrochloride

There total 3 articles about Ethanimidamide, 2,2,2-trifluoro-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

1-Chloro-2,2-dicyanoethylen (10472-09-0) + trifluoroacetamidine (354-37-0,133640-88-7,133640-89-8) → 2-trifluoromethyl-5-cyano-6-aminopyrimidine (943-25-9) + 2,2,2-trifluoroacetimidamide hydrochloride (39560-95-7)

Guidance literature:

In diethyl ether; for 1h;

DOI:10.1007/BF00507001

Reference yield: 62.0%

2-chloro-1,1-dicyano-2-(trifluoromethyl)ethylene (76474-30-1) + trifluoroacetamidine (354-37-0,133640-88-7,133640-89-8) → 2,2,2-trifluoroacetimidamide hydrochloride (39560-95-7) + 2,4-bis(trifluoromethyl)-5-cyano-6-aminopyrimidine (654-50-2)

Guidance literature:

In diethyl ether; for 1h;

DOI:10.1007/BF00507001

Reference yield: 57.0%

1-cyano-1-trifluoromethylthio-2-chloro-2-trifluoromethylethylene (77429-05-1) + trifluoroacetamidine (354-37-0,133640-88-7,133640-89-8) → 2,2,2-trifluoroacetimidamide hydrochloride (39560-95-7) + 2,4-bis(trifluoromethyl)-5-trifluoromethylthio-6-aminopyrimidine (80862-25-5)

Guidance literature:

In diethyl ether; for 1h;

DOI:10.1007/BF00507001

upstream raw materials:

1-Chloro-2,2-dicyanoethylen

trifluoroacetamidine

2-chloro-1,1-dicyano-2-(trifluoromethyl)ethylene

1-cyano-1-trifluoromethylthio-2-chloro-2-trifluoromethylethylene

Downstream raw materials:

5-phenyl-2-(trifluoromethyl)-3H-thieno[2,3-d]pyrimidin-4-one