76474-30-1

Usage

Properties and specific content of 2-(1-chloro-2,2,2-trifluoroethylidene)propanedinitrile (Nitril 2)

A chemical compound consisting of 5 carbon atoms, 2 hydrogen atoms, 1 chlorine atom, 3 fluorine atoms, and 2 nitrogen atoms.

Appearance

Colorless to pale yellow liquid
It is a liquid substance with a color that ranges from colorless to pale yellow.

Boiling point

92-95°C
The compound turns into vapor and boils at a temperature range of 92 to 95 degrees Celsius.

Melting point

-35°C
The compound changes from a liquid to a solid state at a temperature of -35 degrees Celsius.

Density

1.35 g/cm3
The mass of the compound per unit volume is 1.35 grams per cubic centimeter.

Solubility

Slightly soluble in water
The compound does not dissolve easily in water, which may affect its behavior and mobility in the environment.

Highly toxic

Harmful effects on human health
Exposure to 2-(1-chloro-2,2,2- trifluoroethylidene)propanedinitrile can cause respiratory irritation, skin and eye irritation, and potentially more serious health effects with prolonged or high-level exposure.

Flammability

A flammable substance
The compound can easily catch fire and burn, posing a risk of fire or explosion during handling and use.

Environmental impact

Harmful to the environment
As a potent inhibitor of photosynthesis, it can negatively affect plant life and disrupt ecosystems.

Uses

Pesticide and herbicide
The compound is used to control pests and unwanted plant growth in agricultural and non-agricultural settings.

Handling and disposal

Handle with great care
It is essential to handle and dispose of this chemical properly to avoid potential harm to individuals and the environment.

Upstream product

• 431-47-0 trifluoroacetic acid-methyl ester 
• 10026-13-8 phosphorus pentachloride 
• 109-77-3 malononitrile 
• 383-63-1 ethyl trifluoroacetate, 

Downstream Products

• 80862-26-6 1-methyl-2-phenyl-4-trifluoromethyl-5-cyano-6(1H)-pyrimidineimine 
• 41890-09-9 N-methylbenzamidine hydrochloride 
• 82947-36-2 1,1-dicyano-2-bromo-2-(trifluoromethyl)ethylene 
• 76474-36-7 1-(N,N-Dimethylamino)-4-(α-perfluoroheptyl-β,β-dicyanovinyl)-naphthalene 
• 76474-33-4 1,1-dicyano-2-anilino-2-trifluoromethylethylene 
• 39560-95-7 2,2,2-trifluoroacetimidamide hydrochloride 
• 654-50-2 2,4-bis(trifluoromethyl)-5-cyano-6-aminopyrimidine 
• 42563-97-3 trichloroacetamidine hydrochloride 
• 80862-23-3 2-trichloromethyl-4-trifluoromethyl-5-cyano-6-aminopyrimidine 
• 76474-35-6 1-phenyl-3-trifluoromethyl-4-cyano-5-aminopyrazole 
• 128451-11-6 4-(N,N-diethylamino)-α-(trifluoromethyl)-β,β-dicyanostyrene 
• 74-87-3 methylene chloride 
• 75-00-3 chloroethane 
• 148836-81-1 1,1-dicyano-2-diethoxyphosphoryl-2-(trifluoromethyl)ethene 

Relevant academic research and scientific papers

Chlorolysis of β-functionalized alkyl polyfluoroalkenyl sulfides

Chlorolysis of β-functionalized alkyl polyfluoroalkenyl sulfides giving rise to β-functionalized polyfluoroalkenesulfenyl chlorides was examined. β-Cyano-containing sulfenyl chlorides underwent intramolecular cyclization at the nitrile group to form subst

Synthesis and cytotoxic activity of heterocyclization products of 1,1-dicyano-2-hetaryl-2-trifluoromethylethylenes

Methods for the synthesis of novel fluorinated compounds by reaction of 1,1-dicyano-2-hetaryl-2-trifluoromethylethylenes with a variety of nitrogen heterocycles have been developed. Cyctotoxicity of the obtained organofluorine heterocycles were studied in vitro at the U.S. National Cancer Institute (NCI) in the framework of the International Program for Development of Effective Antitumor Drugs. Cytotoxic activity in the series of fluorinated pyrazolo[1,5-a]pyrimidines has been observed for the first time, this strongly depending on the nature and position of the substituents.

6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof

Novel 6-heterocyclyl-pyrazolo[3,4-d]pyrimidin-4-ones, useful in treating cardiovascular disease, are prepared by reacting a 5-amino-1H-pyrazole-4-carboxamide with heterocyclylcarboxaldehyde or by reacting a 5-amino-1H-pyrazole-4-carbonitrile with a heterocyclylcarboxamidine, followed by diazotization and hydrolysis of the resulting 4-amino-6-heterocyclyl-pyrazolo[3,4-d]pyrimidine.

1,1-DICYANO-2-CHLORO-2-TRIFLUOROMETHYLETHYLENE AND ITS TRANSFORMATIONS

The synthesis of 1,1-dicyano-2-chloro-2-trifluoromethylethylene was realized.Its reaction with nucleophilic reagents (alcohols, amines, 1,3,3-trimethyl-2-methyleneindoline, and dimethylaniline) leads to products from substitution of the chlorine atom.For 1,1-dicyano-2-(p-dimethylaminophenyl)ethylenes with various substituents at position 2 a correlation was obtained between the absorption frequency in the electronic spectrum and the ?I and ?R constants of the substituents.