Pyrimidine, 4,6-dichloro-5-(2-chlorophenyl)-

Base Information

Chemical Name:Pyrimidine, 4,6-dichloro-5-(2-chlorophenyl)-
CAS No.:3974-17-2
Molecular Formula:C10H5Cl3N2
Molecular Weight:259.51900
Hs Code.:
Mol file:3974-17-2.mol

Synonyms:4,6-dichloro-5-(2-chloro-phenyl)-pyrimidine;4,6-Dichlor-5-(2-chlorphenyl)-pyrimidin;

Suppliers and Price of Pyrimidine, 4,6-dichloro-5-(2-chlorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Pyrimidine, 4,6-dichloro-5-(2-chlorophenyl)-

Chemical Property:

Melting Point:113 - 114 °C (ethanol)
PSA：25.78000
LogP:4.10380

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Pyrimidine, 4,6-dichloro-5-(2-chlorophenyl)-

There total 5 articles about Pyrimidine, 4,6-dichloro-5-(2-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 3974-13-8
5-(2-chlorophenyl)pyrimidine-4,6-diol

: 3974-17-2
4,6-dichloro-5-(2-chlorophenyl)pyrimidine

Guidance literature:: With trichlorophosphate; at 90 ℃;
DOI:10.1016/j.bmc.2006.12.029

Reference yield:

: 2444-36-2
2'-chloro-benzeneacetic acid

: 3974-17-2
4,6-dichloro-5-(2-chlorophenyl)pyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / conc. HCl / Heating

2: 61 percent / NaH / hexane; tetrahydrofuran / 60 °C

3: 85 percent / NaOEt / ethanol / 60 °C

4: 19 percent / POCl₃ / 90 °C

With hydrogenchloride; sodium ethanolate; sodium hydride; trichlorophosphate; In tetrahydrofuran; ethanol; hexane;
DOI:10.1016/j.bmc.2006.12.029

Reference yield:

: 40061-54-9
2-chlorophenylacetic acid ethyl ester

: 3974-17-2
4,6-dichloro-5-(2-chlorophenyl)pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 61 percent / NaH / hexane; tetrahydrofuran / 60 °C

2: 85 percent / NaOEt / ethanol / 60 °C

3: 19 percent / POCl₃ / 90 °C

With sodium ethanolate; sodium hydride; trichlorophosphate; In tetrahydrofuran; ethanol; hexane;
DOI:10.1016/j.bmc.2006.12.029