2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester

Base Information

Chemical Name:2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester
CAS No.:160776-57-8
Molecular Formula:C₁₅H₁₇N₃O₃
Molecular Weight:287.318
Hs Code.:
DSSTox Substance ID:DTXSID30166981
Nikkaji Number:J618.322K
Wikidata:Q83036276
Mol file:160776-57-8.mol

Synonyms:Ethyl 3,4-dihydro-6-oxo-2H-pyrimido(2,1-b)quinazoline-1(6H)-acetate;2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester;1-Ethoxycarbonylmethyl-6-oxo-1,2,3,4-tetrahydro-6H-pyrimido(2,1-b)quinazoline;160776-57-8;DTXSID30166981;LS-136311;3,4-Dihydro-6-oxo-6H-pyrimido[2,1-b]quinazoline-1(2H)-acetic acid ethyl ester

Suppliers and Price of 2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester

Chemical Property:

Vapor Pressure:5.87E-08mmHg at 25°C
Boiling Point:440.5°Cat760mmHg
Flash Point:220.2°C
Density:1.33g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:287.12699141
Heavy Atom Count:21
Complexity:463

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CN1CCCN2C1=NC3=CC=CC=C3C2=O

Technology Process of 2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester

There total 3 articles about 2H-Pyrimido(2,1-b)quinazoline-1(6H)-acetic acid, 3,4-dihydro-6-oxo-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 19801-37-7
6-oxo-1,2,3,4-tetrahydro-6H-pyrimido<2,1-b>quinazoline

: 105-36-2
ethyl bromoacetate

: 160776-57-8
1-ethoxycarbonylmethyl-6-oxo-1,2,3,4-tetrahydro-6H-pyrimido<2,1-b>quinazoline

Guidance literature:: With potassium carbonate; In benzene; for 10h; Heating;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 160776-57-8
1-ethoxycarbonylmethyl-6-oxo-1,2,3,4-tetrahydro-6H-pyrimido<2,1-b>quinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / 0.17 h / Heating

2: 42 percent / K₂CO₃ / benzene / 10 h / Heating

With potassium carbonate; In benzene;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 160776-57-8
1-ethoxycarbonylmethyl-6-oxo-1,2,3,4-tetrahydro-6H-pyrimido<2,1-b>quinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: Heating

2: potassium carbonate / benzene / 2 h / Heating

With potassium carbonate; In benzene;