9,9-Di-n-butylfluorene-2-boronic acid, 97%

Base Information

• Chemical Name: 9,9-Di-n-butylfluorene-2-boronic acid, 97%
• CAS No.: 400607-56-9
• Molecular Formula: C21H27BO2
• Molecular Weight: 322.255
• Mol file: 400607-56-9.mol

Synonyms:9,9-dibutylfluoreneboronic pinacol ester;Boronic acid,(9,9-dibutyl-9H-fluoren-2-yl);9,9-dibutylfluorene-2-boronic acid;9,9-di(n-butyl)fluorene-2-boronic acid;9,9-bis(n-butyl)-2-fluorenylboronic acid;(9,9-dibutyl-9H-fluoren-2-yl)boronic acid;9,9-dibutyl-fluoren-2-boronic acid;

Chemical Property of 9,9-Di-n-butylfluorene-2-boronic acid, 97%

Chemical Property:

• Boiling Point: 498.9±48.0 °C(Predicted)
• PKA: 8.62±0.40(Predicted)
• PSA: 40.46000
• Density: 1.09±0.1 g/cm3(Predicted)
• LogP: 4.01330

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9,9-Di-n-butylfluorene-2-boronic acid, 97%

There total 6 articles about 9,9-Di-n-butylfluorene-2-boronic acid, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.7%

2-bromo-9,9-di-n-butyl-9H-fluorene (88223-35-2) → (9,9-dibutyl-9H-fluoren-2-yl)boronic acid (400607-56-9)

Guidance literature:

2-bromo-9,9-di-n-butyl-9H-fluorene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 3h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at -78 - 0 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c2ob25926e

Reference yield:

9H-fluorene (86-73-7) → (9,9-dibutyl-9H-fluoren-2-yl)boronic acid (400607-56-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 82 percent / NaOH / dimethylsulfoxide / 90 °C

2.1: 96 percent / NBS / acetone / 3 h / 80 °C

3.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C

3.2: 81 percent / trimethyl borate / tetrahydrofuran / 2 h / -78 °C

With sodium hydroxide; N-Bromosuccinimide; n-butyllithium; In tetrahydrofuran; dimethyl sulfoxide; acetone;

DOI:10.1002/chem.200401152

Reference yield:

9,9-bis(n-butyl)fluorene (15069-42-8) → (9,9-dibutyl-9H-fluoren-2-yl)boronic acid (400607-56-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 96 percent / NBS / acetone / 3 h / 80 °C

2.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C

2.2: 81 percent / trimethyl borate / tetrahydrofuran / 2 h / -78 °C

With N-Bromosuccinimide; n-butyllithium; In tetrahydrofuran; acetone;

DOI:10.1002/chem.200401152

upstream raw materials:

2-bromo-9,9-di-n-butyl-9H-fluorene

9H-fluorene

9,9-bis(n-butyl)fluorene

Trimethyl borate