1H-Pyrazolo[4,3-c]pyridine-1-propanoic acid, 5-[(1,1-dimethylethoxy)carbonyl]-4,5,6,7-tetrahydro-3-[4-(trifluoromethyl) phenyl]-, methyl ester

Base Information

Chemical Name:1H-Pyrazolo[4,3-c]pyridine-1-propanoic acid, 5-[(1,1-dimethylethoxy)carbonyl]-4,5,6,7-tetrahydro-3-[4-(trifluoromethyl) phenyl]-, methyl ester
CAS No.:400797-86-6
Molecular Formula:C22H26F3N3O4
Molecular Weight:453.461
Hs Code.:

1H-Pyrazolo[4,3-c]pyridine-1-propanoic acid,
5-[(1,1-dimethylethoxy)carbonyl]-4,5,6,7-tetrahydro-3-[4-(trifluoromethyl)
phenyl]-, methyl ester

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Pyrazolo[4,3-c]pyridine-1-propanoic acid, 5-[(1,1-dimethylethoxy)carbonyl]-4,5,6,7-tetrahydro-3-[4-(trifluoromethyl) phenyl]-, methyl ester

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Technology Process of 1H-Pyrazolo[4,3-c]pyridine-1-propanoic acid, 5-[(1,1-dimethylethoxy)carbonyl]-4,5,6,7-tetrahydro-3-[4-(trifluoromethyl) phenyl]-, methyl ester

There total 1 articles about 1H-Pyrazolo[4,3-c]pyridine-1-propanoic acid, 5-[(1,1-dimethylethoxy)carbonyl]-4,5,6,7-tetrahydro-3-[4-(trifluoromethyl) phenyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 400797-84-4
3-(4-Trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 400797-86-6
1-(2-methoxycarbonyl-ethyl)-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

Guidance literature:: With sodium t-butanolate; In toluene;

Reference yield:

: 400797-86-6
1-(2-methoxycarbonyl-ethyl)-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

: 400797-87-7
1-(3-Hydroxy-propyl)-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

Guidance literature:: With lithium borohydride; In tetrahydrofuran;

Reference yield:

: 400797-86-6
1-(2-methoxycarbonyl-ethyl)-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

: 400801-20-9
1-(3-Oxo-propyl)-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: lithium borohydride / tetrahydrofuran

2: dichloromethane

With lithium borohydride; In tetrahydrofuran; dichloromethane;