Butanediamide, N-[[1,4-dihydro-1,6-dimethyl-4-oxo-3-(phenylmethoxy)-2-pyridinyl]methyl ]-N'-propyl-

Base Information

Chemical Name:Butanediamide, N-[[1,4-dihydro-1,6-dimethyl-4-oxo-3-(phenylmethoxy)-2-pyridinyl]methyl ]-N'-propyl-
CAS No.:401792-12-9
Molecular Formula:C22H29N3O4
Molecular Weight:399.49
Hs Code.:

Synonyms:

Suppliers and Price of Butanediamide, N-[[1,4-dihydro-1,6-dimethyl-4-oxo-3-(phenylmethoxy)-2-pyridinyl]methyl ]-N'-propyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Butanediamide, N-[[1,4-dihydro-1,6-dimethyl-4-oxo-3-(phenylmethoxy)-2-pyridinyl]methyl ]-N'-propyl-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Butanediamide, N-[[1,4-dihydro-1,6-dimethyl-4-oxo-3-(phenylmethoxy)-2-pyridinyl]methyl ]-N'-propyl-

There total 8 articles about Butanediamide, N-[[1,4-dihydro-1,6-dimethyl-4-oxo-3-(phenylmethoxy)-2-pyridinyl]methyl ]-N'-propyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 61283-60-1
4-(propylamino)-4-oxobutanoic acid

: 401792-02-7
2-(aminomethyl)-1,6-dimethyl-3-(phenylmethoxy)-4(1H)-pyridinone

: 401792-12-9
1,6-dimethyl-2-(4'-N-n-propylsuccinamido)methyl-3-benzyloxypyridin-4(1H)-one

Guidance literature:: In dichloromethane; for 6h; Heating;
DOI:10.1021/jm010817i

Reference yield:

: 501-30-4,123712-78-7
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

: 401792-12-9
1,6-dimethyl-2-(4'-N-n-propylsuccinamido)methyl-3-benzyloxypyridin-4(1H)-one

Guidance literature:: Multi-step reaction with 10 steps

1.1: SOCl₂

2.1: Zn; HCl

3.1: 82 percent / aq. NaOH / 12 h / 20 °C

4.1: aq. NaOH / methanol / Heating

4.2: 80 percent / methanol / 12 h / Heating

5.1: p-TsOH*H₂O / CH₂Cl₂ / 3 h / 20 °C

6.1: ethanol; H₂O / 12 h / 70 °C

7.1: 2.15 g / 2 N aq. HCl / ethanol / 4 h / Heating

8.1: 80 percent / PPh₃; diethyl azodicarboxylate / tetrahydrofuran / 20 °C

9.1: 92 percent / 5.5percent aq. hydrazine / ethanol / 3 h / Heating

10.1: 100 percent / CH₂Cl₂ / 6 h / Heating

With hydrogenchloride; sodium hydroxide; thionyl chloride; toluene-4-sulfonic acid; triphenylphosphine; zinc; diethylazodicarboxylate; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;
DOI:10.1021/jm010817i

Reference yield:

: 644-46-2
allomaltol

: 401792-12-9
1,6-dimethyl-2-(4'-N-n-propylsuccinamido)methyl-3-benzyloxypyridin-4(1H)-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: 82 percent / aq. NaOH / 12 h / 20 °C

2.1: aq. NaOH / methanol / Heating

2.2: 80 percent / methanol / 12 h / Heating

3.1: p-TsOH*H₂O / CH₂Cl₂ / 3 h / 20 °C

4.1: ethanol; H₂O / 12 h / 70 °C

5.1: 2.15 g / 2 N aq. HCl / ethanol / 4 h / Heating

6.1: 80 percent / PPh₃; diethyl azodicarboxylate / tetrahydrofuran / 20 °C

7.1: 92 percent / 5.5percent aq. hydrazine / ethanol / 3 h / Heating

8.1: 100 percent / CH₂Cl₂ / 6 h / Heating

With hydrogenchloride; sodium hydroxide; toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;
DOI:10.1021/jm010817i