tert-Butyl 8-hydroxyoctanoate

Base Information

Chemical Name:tert-Butyl 8-hydroxyoctanoate
CAS No.:401901-41-5
Molecular Formula:C12H24O3
Molecular Weight:216.321
Hs Code.:
European Community (EC) Number:867-719-7

Synonyms:tert-Butyl 8-hydroxyoctanoate;401901-41-5;tert-Butyl8-Hydroxyoctanoate;t-butyl-8-hydroxyoctanoate;Octanoic acid, 8-hydroxy-, 1,1-dimethylethyl ester;C12H24O3;SCHEMBL3988979;BFFNOXGQNLNKTJ-UHFFFAOYSA-N;MFCD30472716;AKOS037649182;AT11174;BS-17012;DB-145548;CS-0129686;EN300-171057;A1-23335

Suppliers and Price of tert-Butyl 8-hydroxyoctanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of tert-Butyl 8-hydroxyoctanoate

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:216.17254462
Heavy Atom Count:15
Complexity:170

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CCCCCCCO

Technology Process of tert-Butyl 8-hydroxyoctanoate

There total 5 articles about tert-Butyl 8-hydroxyoctanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 234081-94-8
suberic acid mono-tert-butyl ester

: 401901-41-5
tert-butyl 8-hydroxyoctanoate

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 20 ℃; for 24h;

Reference yield:

: 3946-32-5
suberic acid monomethyl ester

: 401901-41-5
tert-butyl 8-hydroxyoctanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / (Boc)2O; 4-(dimethylamino)pyridine / 1 h / 20 °C

2: NaOH / tetrahydrofuran; methanol; H₂O / 28 h / 20 °C

3: BH₃*THF / tetrahydrofuran / 24 h / 0 - 20 °C

With dmap; sodium hydroxide; borane-THF; di-tert-butyl dicarbonate; In tetrahydrofuran; methanol; water;
DOI:10.1016/j.tet.2006.06.088

Reference yield:

: 137299-08-2
tert-butyl 7-(methoxycarbonyl)heptanoate

: 401901-41-5
tert-butyl 8-hydroxyoctanoate

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / tetrahydrofuran; methanol; H₂O / 28 h / 20 °C

2: BH₃*THF / tetrahydrofuran / 24 h / 0 - 20 °C

With sodium hydroxide; borane-THF; In tetrahydrofuran; methanol; water;
DOI:10.1016/j.tet.2006.06.088