2-(Thiophen-3-ylmethyl)propanedioic acid

Base Information

Chemical Name:2-(Thiophen-3-ylmethyl)propanedioic acid
CAS No.:26415-26-9
Molecular Formula:C8H8 O4 S
Molecular Weight:200.215
Hs Code.:
European Community (EC) Number:842-742-5
NSC Number:109416
DSSTox Substance ID:DTXSID70296453
Wikidata:Q82037067

Synonyms:2-(thiophen-3-ylmethyl)propanedioic acid;26415-26-9;2-[(thiophen-3-yl)methyl]propanedioic acid;NSC109416;SCHEMBL10805875;DTXSID70296453;BBA41526;AKOS026729577;NSC-109416;2-(thiophen-3-ylmethyl)propanedioicacid;EN300-129443;Z1269224459

Suppliers and Price of 2-(Thiophen-3-ylmethyl)propanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(Thiophen-3-ylmethyl)propanedioic acid

Chemical Property:

Vapor Pressure:6.05E-07mmHg at 25°C
Boiling Point:394.9°Cat760mmHg
Flash Point:192.6°C
Density:1.489g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:200.01432991
Heavy Atom Count:13
Complexity:202

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC=C1CC(C(=O)O)C(=O)O

Technology Process of 2-(Thiophen-3-ylmethyl)propanedioic acid

There total 6 articles about 2-(Thiophen-3-ylmethyl)propanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 26415-25-8
3-thiophen-3-yl methyl malonic acid diethyl ester

: 26415-26-9
[3]thienylmethyl-malonic acid

Guidance literature:: With sodium hydroxide; hydrogen cation; 1.) EtOH; 2.) H₂O;

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: C₂₂H₃₄B₂S

: 26415-26-9
[3]thienylmethyl-malonic acid

Guidance literature:: carbon dioxide; C₂₂H₃₄B₂S; With copper(l) iodide; 1,3-bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene hydrochloride; cesium fluoride; at 120 ℃; for 16h;

With hydrogenchloride; In water;
DOI:10.1021/acscatal.6b03571

Reference yield:

: 34846-44-1
3-Bromomethylthiophene

: 26415-26-9
[3]thienylmethyl-malonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / NaH / tetrahydrofuran

2: 70 percent / KOH / H₂O / Heating

With potassium hydroxide; sodium hydride; In tetrahydrofuran; water;
DOI:10.1016/S0040-4020(97)00151-8