5-Chloro-2-iodo-M-xylene

Base Information

• Chemical Name: 5-Chloro-2-iodo-M-xylene
• CAS No.: 404337-42-4
• Molecular Formula: C8H8ClI
• Molecular Weight: 266.509
• Mol file: 404337-42-4.mol

Synonyms:4-chloro-2,6-dimethyliodobenzene;5-CHLORO-2-IODO-1,3-DIMETHYLBENZENE;

Chemical Property of 5-Chloro-2-iodo-M-xylene

Chemical Property:

• PSA: 0.00000
• LogP: 3.56140
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98.5% ^*data from raw suppliers

5-Chloro-2-iodo-m-xylene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Chloro-2-iodo-M-xylene

There total 1 articles about 5-Chloro-2-iodo-M-xylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

4-chloro-2,6-dimethylaniline (24596-18-7) → 4-chloro-1-iodo-2,6-dimethylbenzene (404337-42-4)

Guidance literature:

With hydrogenchloride; potassium iodide; sodium nitrite; In water; Reflux; Inert atmosphere;

DOI:10.1021/jm8000778

Reference yield: 78.0%

4-chloro-1-iodo-2,6-dimethylbenzene (404337-42-4) → 5-chloro-2-iodo-isophthalic acid (1071986-18-9)

Guidance literature:

With potassium permanganate; at 115 ℃; for 8h;

Reference yield: 67.0%

copper(I) cyanide (544-92-3) + 4-chloro-1-iodo-2,6-dimethylbenzene (404337-42-4) → 4-chloro-2,6-dimethylbenzonitrile (5757-67-5)

Guidance literature:

In N,N-dimethyl-formamide;

DOI:10.1246/bcsj.74.2207

upstream raw materials:

4-chloro-2,6-dimethylaniline

Downstream raw materials:

bis(4-chloro-2,6-dimethylphenyl)ketimine

4-chloro-2,6-dimethylbenzonitrile

diazobis(4-chloro-2,6-dimethylphenyl)methane

1-(4-chloro-2,6-dimethylphenyl)propan-1-ol

Refernces

• 1、 Hu, Yingmo,Ishikawa, Yui,Hirai, Katsuyuki,Tomioka, Hideo. "Spectroscopic and product studies of the effect of para substituents on the reactivity of triplet bis(2,6-dimethylphenyl)carbenes". . p. 2207 - 2218. Retrieved 2007/10/03.