1-(2,4-difluorobenzyl)-3-formyl-1H-indole

Base Information

Chemical Name:1-(2,4-difluorobenzyl)-3-formyl-1H-indole
CAS No.:405274-90-0
Molecular Formula:C16H11F2NO
Molecular Weight:271.26100
Hs Code.:
Mol file:405274-90-0.mol

Synonyms:1-(2,4-difluorobenzyl)-3-formylindole;1-(2,4-Difluoro-benzyl)-1H-indole-3-carbaldehyde;

Suppliers and Price of 1-(2,4-difluorobenzyl)-3-formyl-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(2,4-difluorobenzyl)-3-formyl-1H-indole

Chemical Property:

Melting Point:120 - 121 °C (di-isopropyl ether)
PSA：22.00000
LogP:3.78030

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2,4-difluorobenzyl)-3-formyl-1H-indole

There total 3 articles about 1-(2,4-difluorobenzyl)-3-formyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 452-07-3
2,4-difluorobenzyl chloride

: 405274-90-0
1-(2,4-difluorobenzyl)-3-formyl-1H-indole

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 2h;
DOI:10.1016/S0223-5234(02)00005-3

Reference yield: 83.0%

: 405274-90-0
1-(2,4-difluorobenzyl)-3-formyl-1H-indole

Guidance literature:

Reference yield:

: 120-72-9
indole

: 405274-90-0
1-(2,4-difluorobenzyl)-3-formyl-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate

2: sodium hydride / dimethyl sulfoxide

With sodium hydride; trichlorophosphate; In dimethyl sulfoxide;
DOI:10.5012/bkcs.2011.32.1.307