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452-07-3

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452-07-3 Usage

Description

2,4-Difluorobenzyl chloride, an organic compound with the chemical formula C7H5ClF2, is a colorless liquid characterized by a strong and pungent odor. It serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, as well as a reagent in organic synthesis, particularly for the preparation of fluorinated compounds. Its ability to introduce fluorine atoms into organic molecules makes it a valuable compound in the pharmaceutical and agrochemical industries.

Uses

Used in Pharmaceutical Industry:
2,4-Difluorobenzyl chloride is used as an intermediate for the synthesis of various pharmaceutical compounds. Its ability to introduce fluorine atoms into organic molecules enhances the properties of the resulting pharmaceuticals, such as their bioavailability, metabolic stability, and receptor binding affinity.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4-Difluorobenzyl chloride is utilized as a building block for the development of new agrochemicals. The incorporation of fluorine atoms into these compounds can improve their effectiveness, selectivity, and environmental persistence.
Used in Organic Synthesis:
2,4-Difluorobenzyl chloride is used as a reagent in organic synthesis for the preparation of various fluorinated compounds. Its versatility in chemical reactions allows for the creation of a wide range of organic molecules with potential applications in various fields.
Used in Fluorination Reactions:
As a valuable compound for introducing fluorine atoms into organic molecules, 2,4-Difluorobenzyl chloride is employed in fluorination reactions. This process can significantly alter the properties of the target molecules, leading to improved performance in various applications, such as drug development and material science.

Check Digit Verification of cas no

The CAS Registry Mumber 452-07-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 452-07:
(5*4)+(4*5)+(3*2)+(2*0)+(1*7)=53
53 % 10 = 3
So 452-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClF2/c8-4-5-1-2-6(9)3-7(5)10/h1-3H,4H2

452-07-3 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (H26783)  2,4-Difluorobenzyl chloride, 97%   

  • 452-07-3

  • 5g

  • 1790.0CNY

  • Detail
  • Alfa Aesar

  • (H26783)  2,4-Difluorobenzyl chloride, 97%   

  • 452-07-3

  • 25g

  • 5495.0CNY

  • Detail

452-07-3Relevant articles and documents

2. 4 - difluorobenzene methylamine synthetic method

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Paragraph 0036-0040, (2017/10/22)

The invention relates to the fields of medicine and agrochemicals, and concretely relates to a synthetic method of an intermediate 2,4-difluorobenzene methylamine. The synthetic method comprises the following steps: 1) m-difluorobenzene, a halogenating agent and paraformaldehyde are reacted under effect of a catalyst to prepare 2,4-difluoro benzyl halide; 2)the prepared 2,4-difluoro benzyl halide and urotropine are reacted to prepare a quaternary ammonium salt compound IV; 3)the prepared quaternary ammonium salt compound is hydrolyzed by concentrated hydrochloric acid to obtain 2,4-difluorobenzene methylamine. The method has the advantages of low cost of the prepared 2,4-difluorobenzene methylamine, convenient operation and high security coefficient, and is suitable for industrial production.

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