6-{[(4-methoxyphenyl)sulfanyl]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine

Base Information

• Chemical Name: 6-{[(4-methoxyphenyl)sulfanyl]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
• CAS No.: 159210-74-9
• Molecular Formula: C₁₆H₁₇N₅OS
• Molecular Weight: 327.41

Synonyms:Pyrido(2,3-d)pyrimidine-2,4-diamine,6-(((4-methoxyphenyl)thio)methyl)-5-methyl;

Chemical Property of 6-{[(4-methoxyphenyl)sulfanyl]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine

Chemical Property:

• Vapor Pressure: 9.48E-16mmHg at 25°C
• Boiling Point: 629.3°C at 760 mmHg
• Flash Point: 334.4°C
• PSA: 126.70000
• Density: 1.37g/cm³
• LogP: 2.65870

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-{[(4-methoxyphenyl)sulfanyl]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine

There total 1 articles about 6-{[(4-methoxyphenyl)sulfanyl]methyl}-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methoxybenzenethiol (696-63-9) + 6-(bromomethyl)-2,4-diamino-5-methylpyrido<2,3-d>pyrimidine hydrobromide → 6-(4-Methoxy-phenylsulfanylmethyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine (159210-74-9)

Guidance literature:

With potassium carbonate; Multistep reaction; 1.) Me₂NAc, from 20 deg C to 23 deg C, 2 h, 2.) Me₂NAc, 24 h;

DOI:10.1021/jm950760y

upstream raw materials:

4-Methoxybenzenethiol

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