N-[4-(3-Bromo-propoxy)-phenyl]-acetamide

Base Information

Chemical Name:N-[4-(3-Bromo-propoxy)-phenyl]-acetamide
CAS No.:40981-73-5
Molecular Formula:C11H14BrNO2
Molecular Weight:272.142
Hs Code.:
DSSTox Substance ID:DTXSID10445827
Wikidata:Q82264358
Mol file:40981-73-5.mol

Synonyms:Acetamide, N-[4-(3-bromopropoxy)phenyl]-;40981-73-5;N-[4-(3-BROMO-PROPOXY)-PHENYL]-ACETAMIDE;N-[4-(3-bromopropoxy)phenyl]acetamide;N-(4-(3-Bromopropoxy)phenyl)acetamide;SCHEMBL3102351;DTXSID10445827;GYQVTCSDOJTHEB-UHFFFAOYSA-N

Suppliers and Price of N-[4-(3-Bromo-propoxy)-phenyl]-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of N-[4-(3-Bromo-propoxy)-phenyl]-acetamide

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:271.02079
Heavy Atom Count:15
Complexity:191

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)OCCCBr

Technology Process of N-[4-(3-Bromo-propoxy)-phenyl]-acetamide

There total 3 articles about N-[4-(3-Bromo-propoxy)-phenyl]-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 103-90-2,8055-08-1
4-acetaminophenol

: 109-64-8
1,3-dibromo-propane

: 40981-73-5
acetic acid-[4-(3-bromo-propoxy)-anilide]

Guidance literature:: With potassium carbonate; In acetonitrile; for 24h; Reflux; Inert atmosphere;
DOI:10.1039/d1cc02134f

Reference yield:

: 2623-33-8
4-acetoxyacetanilide

: 40981-73-5
acetic acid-[4-(3-bromo-propoxy)-anilide]

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / methanol / 24 h / 50 °C

2: triethylamine; potassium carbonate / acetone / 6 h / Reflux

With potassium carbonate; triethylamine; sodium hydroxide; In methanol; acetone;
DOI:10.1016/j.bmcl.2020.127506

Reference yield:

: 123-30-8
4-amino-phenol

: 40981-73-5
acetic acid-[4-(3-bromo-propoxy)-anilide]

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 6 h / 20 °C / Cooling with ice

2: sodium hydroxide / methanol / 24 h / 50 °C

3: triethylamine; potassium carbonate / acetone / 6 h / Reflux

With potassium carbonate; triethylamine; sodium hydroxide; In methanol; dichloromethane; acetone;
DOI:10.1016/j.bmcl.2020.127506