Cyclooct-3-en-1-ol

Base Information

• Chemical Name: Cyclooct-3-en-1-ol
• CAS No.: 4114-99-2
• Molecular Formula: C8H14O
• Molecular Weight: 126.199
• DSSTox Substance ID: DTXSID50701994
• Mol file: 4114-99-2.mol

Synonyms:cyclooctene-4-ol;4114-99-2;Cyclooct-3-en-1-ol;DTXSID50701994;PKZBRYXOYZUZIR-UHFFFAOYSA-N

Chemical Property of Cyclooct-3-en-1-ol

Chemical Property:

• PSA: 20.23000
• LogP: 1.86760
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 126.104465066
• Heavy Atom Count: 9
• Complexity: 96.7

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC=CC1)O

Technology Process of Cyclooct-3-en-1-ol

There total 5 articles about Cyclooct-3-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclooctene oxide (286-62-4) → cycloactanone (502-49-8) + oct-7-enal (21573-31-9) + cycloheptanecarboxaldehyde (4277-29-6) + 3-cyclohexenol (4114-99-2)

Guidance literature:

iron(II) sulfate; at 108 ℃; for 2h; Yield given. Further byproducts given;

DOI:10.1246/bcsj.67.2351

Reference yield:

Cyclooctene oxide (286-62-4) → cycloactanone (502-49-8) + (Z)-2-cycloocten-1-ol (62249-35-8) + cycloheptanecarboxaldehyde (4277-29-6) + 3-cyclohexenol (4114-99-2)

Guidance literature:

titanium(IV) oxide; zirconium(IV) oxide; at 108 ℃; for 6h; Yield given;

DOI:10.1246/bcsj.67.2351

Reference yield:

Cyclooctene oxide (286-62-4) → cycloactanone (502-49-8) + oct-7-enal (21573-31-9) + (Z)-2-cycloocten-1-ol (62249-35-8) + cycloheptanecarboxaldehyde (4277-29-6) + 3-cyclohexenol (4114-99-2)

Guidance literature:

silica gel; titanium(IV) oxide; In toluene; at 108 ℃; for 0.5h; Product distribution; other catalysts, var. time;

DOI:10.1246/bcsj.67.2351

upstream raw materials:

cis-1,4-dihydroxycyclooctane

Cyclooctene oxide

1,4-cyclooctadiene

Downstream raw materials:

9-Oxa-bicyclo[6.1.0]nonan-3-ol

9-oxa-bicyclo[6.1.0]nonan-3-ol

3,4-epoxycyclooctanol

10,11,12,13-Tetraphenyl-3-oxatricyclo<7.4.0.0^2,4>trideca-1(9),10,12-trien