Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]-

Base Information

Chemical Name:Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]-
CAS No.:412015-25-9
Molecular Formula:C15H14N2O3S
Molecular Weight:302.354
Hs Code.:
DSSTox Substance ID:DTXSID00449379
Pharos Ligand ID:MBVBN7SC76XZ
ChEMBL ID:CHEMBL2113054
Mol file:412015-25-9.mol

Synonyms:412015-25-9;Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]-;SCHEMBL1645802;CHEMBL2113054;DTXSID00449379

Suppliers and Price of Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:302.07251349
Heavy Atom Count:21
Complexity:386

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)SC2=CC=CC=C2C(=O)NC)[N+](=O)[O-]

Technology Process of Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]-

There total 5 articles about Benzamide, N-methyl-2-[(4-methyl-2-nitrophenyl)thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 593-51-1
methylamine hydrochloride

: 2-(4'-methyl-2'-nitrophenylthio)benzoic acid chloride

: 412015-25-9
N-methyl-2-(4'-methyl-2'-nitrophenylthio)benzamide

Guidance literature:: With triethylamine; In dichloromethane; at -70 ℃;

Reference yield:

: 860778-56-9
ethyl 2-(4'-methyl-2'-nitrophenylthio)benzoate

: 412015-25-9
N-methyl-2-(4'-methyl-2'-nitrophenylthio)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / aq. NaOH / 0.33 h / 120 °C

2: SOCl₂; DMF / CH₂Cl₂ / 1.5 h / Heating

3: 0.67 g / Et₃N / CH₂Cl₂ / -70 - 20 °C

With sodium hydroxide; thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jm050079o

Reference yield:

: 5326-34-1
4-Bromo-3-nitrotoluene

: 412015-25-9
N-methyl-2-(4'-methyl-2'-nitrophenylthio)benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 58 percent / Cs₂CO₃; CuI / toluene / Heating

2: 98 percent / aq. NaOH / 0.33 h / 120 °C

3: SOCl₂; DMF / CH₂Cl₂ / 1.5 h / Heating

4: 0.67 g / Et₃N / CH₂Cl₂ / -70 - 20 °C

With sodium hydroxide; copper(l) iodide; thionyl chloride; caesium carbonate; triethylamine; N,N-dimethyl-formamide; In dichloromethane; toluene;
DOI:10.1021/jm050079o