3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione
CAS No.:4260-41-7
Molecular Formula:C₁₁H₁₀N₂O₂
Molecular Weight:202.213
Hs Code.:
DSSTox Substance ID:DTXSID80551429
Nikkaji Number:J1.805.436A
Wikidata:Q82431089
Mol file:4260-41-7.mol

Synonyms:3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione;4260-41-7;3-(4-methylphenyl)-1H-pyrimidine-2,4-dione;3-(4-Methylphenyl)pyrimidine-2,4(1H,3H)-dione;SCHEMBL5325747;DTXSID80551429;AKOS026713596;F1967-2294

Suppliers and Price of 3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:202.074227566
Heavy Atom Count:15
Complexity:304

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2C(=O)C=CNC2=O

Technology Process of 3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione

There total 3 articles about 3-(p-tolyl)pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 113094-25-0
(1R,2R,7S,8S)-5-p-Tolyl-3,5-diaza-tricyclo[6.2.1.0^2,7]undec-9-ene-4,6-dione

: 4260-41-7
3-(4-methylphenyl)-2,3-dihydropyrimidin-4(1H)-one

Guidance literature:: for 0.166667h; Heating;
DOI:10.1016/S0040-4020(01)81504-0

Reference yield:

: 622-51-5
p-tolylurea

: 122-51-0
orthoformic acid triethyl ester

Polymer: 4-phenylbutan-2-one cyclic malonic acid ester, bound to Merrifield resin: Polymer: 4-phenylbutan-2-one cyclic malonic acid ester, bound to Merrifield resin

: 4260-41-7
3-(4-methylphenyl)-2,3-dihydropyrimidin-4(1H)-one

Guidance literature:: orthoformic acid triethyl ester; Polymer: 4-phenylbutan-2-one cyclic malonic acid ester, bound to Merrifield resin; for 6h; Heating;

p-tolylurea; for 12h; Heating;

at 220 - 240 ℃; for 0.333333h; Further stages.;
DOI:10.1021/jo020175m

Reference yield:

: 109853-40-9
(1S,2S,3R,4R)-3-Amino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid p-tolylamide

: 4260-41-7
3-(4-methylphenyl)-2,3-dihydropyrimidin-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / benzene / 8 h / Heating

2: 80 percent / 0.17 h / Heating

In benzene;
DOI:10.1016/S0040-4020(01)81504-0