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622-51-5

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622-51-5 Usage

Chemical Properties

beige crystalline powder

General Description

Colorless crystals.

Reactivity Profile

P-TOLYLUREA is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

ACUTE/CHRONIC HAZARDS: Slightly toxic. Hazardous decomposition products.

Purification Methods

Crystallise the urea from H2O (m 186o), EtOH/water (1:1) or aqueous AcOH (m 184o). [Beilstein 12 H 941, 12 I 425, 12 II 512, 12 III 2084, 12 IV 1923.]

Check Digit Verification of cas no

The CAS Registry Mumber 622-51-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 622-51:
(5*6)+(4*2)+(3*2)+(2*5)+(1*1)=55
55 % 10 = 5
So 622-51-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O/c1-6-2-4-7(5-3-6)10-8(9)11/h2-5H,1H3,(H3,9,10,11)

622-51-5 Well-known Company Product Price

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  • (Code)Product description
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  • TCI America

  • (T0328)  p-Tolylurea  >98.0%(HPLC)

  • 622-51-5

  • 25g

  • 690.00CNY

  • Detail
  • Alfa Aesar

  • (A11150)  p-Tolylurea, 98+%   

  • 622-51-5

  • 25g

  • 611.0CNY

  • Detail
  • Alfa Aesar

  • (A11150)  p-Tolylurea, 98+%   

  • 622-51-5

  • 100g

  • 1728.0CNY

  • Detail
  • Alfa Aesar

  • (A11150)  p-Tolylurea, 98+%   

  • 622-51-5

  • 500g

  • 7244.0CNY

  • Detail

622-51-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-methylphenyl)urea

1.2 Other means of identification

Product number -
Other names Urea, (4-methylphenyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:622-51-5 SDS

622-51-5Relevant articles and documents

Reaction of N-arylcarbamoyl-1,4-benzoquinone imines with sodium arenesulfinates

Konovalova,Avdeenko,Sergeeva,Menafova

, (2014)

N-Arylcarbamoyl-1,4-benzoquinone imines possessing at least one free ortho position with respect to the carbonyl carbon atom in the quinoid ring react with sodium arenesulfinates according to the nucleophilic 1,4-addition pattern with complete regioselect

Synthesis of Five-Membered Cyclic Guanidines via Cascade [3 + 2] Cycloaddition of α-Haloamides with Organo-cyanamides

Wang, Chuan-Chuan,Qu, Ya-Li,Liu, Xue-Hua,Ma, Zhi-Wei,Yang, Bo,Liu, Zhi-Jing,Chen, Xiao-Pei,Chen, Ya-Jing

, p. 3546 - 3554 (2021/02/16)

The convenient preparation of N2-unprotected five-membered cyclic guanidines was achieved through a cascade [3 + 2] cycloaddition between organo-cyanamides and α-haloamides under mild conditions in good to excellent yields (up to 99%). The corresponding cyclic guanidines could be easily transformed into hydantoins via hydrolysis.

Dual palladium-photoredox catalyzed chemoselective C-H arylation of phenylureas

Babu, Sakamuri Sarath,Shahid,Gopinath, Purushothaman

supporting information, p. 5985 - 5988 (2020/06/04)

A highly chemoselective C-H arylation of phenylureas has been accomplished using dual palladium-photoredox catalysis at room temperature without any additives, base or external oxidants. Regioselective C-H arylation ofN,N'-diaryl substituted unsymmetrical phenylureas has also been accomplished by a careful choice of aryl groups.

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