1,1'-Biphenyl, 4-[(1Z)-2-[1,1'-biphenyl]-4-ylethenyl]-4'-(isocyanatomethyl)-

Base Information

Chemical Name:1,1'-Biphenyl, 4-[(1Z)-2-[1,1'-biphenyl]-4-ylethenyl]-4'-(isocyanatomethyl)-
CAS No.:427879-56-9
Molecular Formula:C28H21NO
Molecular Weight:387.481
Hs Code.:

Synonyms:

Suppliers and Price of 1,1'-Biphenyl, 4-[(1Z)-2-[1,1'-biphenyl]-4-ylethenyl]-4'-(isocyanatomethyl)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1'-Biphenyl, 4-[(1Z)-2-[1,1'-biphenyl]-4-ylethenyl]-4'-(isocyanatomethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,1'-Biphenyl, 4-[(1Z)-2-[1,1'-biphenyl]-4-ylethenyl]-4'-(isocyanatomethyl)-

There total 10 articles about 1,1'-Biphenyl, 4-[(1Z)-2-[1,1'-biphenyl]-4-ylethenyl]-4'-(isocyanatomethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 75-44-5
phosgene

: 427879-54-7
(Z)-1-[4'-(2-biphenyl-4-yl-vinyl)-biphenyl-4-yl]methylamine

: 427879-56-9
(Z)-1-[4'-(2-biphenyl-4-yl-vinyl)-biphenyl-4-yl]methyl isocyanate

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; water; toluene; at 0 ℃; for 0.333333h;
DOI:10.1021/ja017577g

Reference yield:

: 353739-79-4
(Z)-1-[2-(4-bromo-phenyl)]-biphenyl-ethene

: 427879-56-9
(Z)-1-[4'-(2-biphenyl-4-yl-vinyl)-biphenyl-4-yl]methyl isocyanate

Guidance literature:: Multi-step reaction with 5 steps

1.1: tert-butyllithium / tetrahydrofuran; pentane / 1 h / -78 °C

1.2: zinc chloride / tetrahydrofuran; pentane / 1.5 h / 23 °C

1.3: tetrakis(triphenylphosphine)palladium⁽⁰⁾ / tetrahydrofuran; pentane / 18 h / Heating

2.1: 1.54 g / n-tetrabutylammonium fluoride / tetrahydrofuran / 1.5 h

3.1: 91 percent / triphenylphosphine; DEAD / tetrahydrofuran / 1 h / 0 °C

4.1: 100 percent / hydrazine monohydrate / tetrahydrofuran; ethanol / Heating

5.1: 96 percent / aq. NaHCO₃ / CH₂Cl₂; toluene / 0.33 h / 0 °C

With tetrabutyl ammonium fluoride; tert.-butyl lithium; sodium hydrogencarbonate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane; toluene; pentane;
DOI:10.1021/ma020155m

Reference yield:

: 59016-93-2
p-hydroxymethylphenylboronic acid

: 427879-56-9
(Z)-1-[4'-(2-biphenyl-4-yl-vinyl)-biphenyl-4-yl]methyl isocyanate

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / terakis(triphenylphosphine)palladium⁽⁰⁾; aq. Na₂CO₃ / tetrahydrofuran / 21 h / Heating

2: 91 percent / triphenylphosphine; DEAD / tetrahydrofuran / 1 h / 0 °C

3: 100 percent / hydrazine monohydrate / tetrahydrofuran; ethanol / Heating

4: 96 percent / aq. NaHCO₃ / CH₂Cl₂; toluene / 0.33 h / 0 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; sodium carbonate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; dichloromethane; toluene;
DOI:10.1021/ma020155m